Objective COMPAR-EU aims to identify, compare, and rank the most effective and cost-effective self-management interventions (SMIs) for adults in Europe within four high-priority chronic conditions: type 2 diabetes, obesity, chronic obstructive pulmonary disease, and heart failure. This project addresses an important gap in current knowledge applying network meta-analysis, an extension of meta-analysis methodology that allows multiple (rather than pairwise) comparisons of intervention effectiveness, to randomised controlled trials (RCTs) that meet the study inclusion criteria. This centralised analysis of an estimated 4000 RCTs will substantially help to overcome current problems associated with the dispersion and duplication of evidence. The work will be based on a validated taxonomy of SMIs and will prioritise outcomes from the patients’ perspective. In addition, a cost-effectiveness of the most effective SMIs will be estimated to provide insights into the economic consequences of adopting SMIs for societies, healthcare budgets, and patients. Contextual factors associated with successful interventions will also be studied. Drawing on our results, we will develop and pilot decision-making tools to facilitate access to evidence-based information on the most effective SMIs to key users through a user-friendly interactive platform. A multiprong strategy for exploitation of the research findings will lead to clear business cases for implementing it in different contexts within the heterogeneous EU health system.The end goal of the project is to have an impact in supporting policy-makers, guideline developers, researchers, industry, professionals and patients to make informed decisions on the identification and implementation of the most suitable SMIs, therefore contributing to the diffusion of the knowledge, healthcare sustainability and equity and promoting EU competitiveness in a globally emerging market. Fields of science medical and health sciencesclinical medicineendocrinologydiabetesmedical and health scienceshealth sciencesinfectious diseasesRNA virusesHIVsocial scienceseconomics and businesseconomicsproduction economicsproductivitymedical and health sciencesclinical medicinecardiologymedical and health scienceshealth sciencesnutritionobesity Keywords self-management network meta-analysis decision-making Programme(s) H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme H2020-EU.3.1.3. - Treating and managing disease Topic(s) SC1-PM-10-2017 - Comparing the effectiveness of existing healthcare interventions in the adult population Call for proposal H2020-SC1-2016-2017 See other projects for this call Sub call H2020-SC1-2017-Two-Stage-RTD Funding Scheme RIA - Research and Innovation action Coordinator FUNDACION AVEDIS DONABEDIAN PARA LA MEJORA DE LA CALIDAD ASISTENCIAL Net EU contribution € 1 351 930,00 Address CALLE PROVENZA 293 PRAL 08037 Barcelona Spain See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Este Cataluña Barcelona Activity type Other Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 1 351 930,00 Participants (7) Sort alphabetically Sort by Net EU contribution Expand all Collapse all FORUM DES PATIENTS EUROPEENS Belgium Net EU contribution € 477 458,75 Address CHAUSSEE D ETTERBEEK 180 BRUSSELS Brussels / Bruxelles See on map Activity type Other Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 477 458,75 INSTITUTE FOR MEDICAL TECHNOLOGY ASSESSMENT BV Netherlands Net EU contribution € 698 535,00 Address BURGEMEESTER OUDLAAN 50 3062PA Rotterdam See on map Region West-Nederland Zuid-Holland Groot-Rijnmond Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 776 600,00 Third-party Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure. ERASMUS UNIVERSITEIT ROTTERDAM Netherlands Net EU contribution € 78 065,00 Address BURGEMEESTER OUDLAAN 50 3062 PA Rotterdam See on map Region West-Nederland Zuid-Holland Groot-Rijnmond Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 78 065,00 STICHTING NEDERLANDS INSTITUUT VOOR ONDERZOEK VAN DE GEZONDHEIDSZORG Netherlands Net EU contribution € 1 278 120,00 Address OTTERSTRAAT 118-124 3500 BN Utrecht See on map Region West-Nederland Utrecht Utrecht Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 1 278 120,00 INSTITUT DE RECERCA DE L'HOSPITAL DE LA SANTA CREU I SANT PAU FUNDACION Spain Net EU contribution € 777 786,25 Address C SANT QUINTI 77-79 08041 Barcelona See on map Region Este Cataluña Barcelona Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 777 786,25 OPTIMEDIS AG Germany Net EU contribution € 733 796,25 Address BURCHARDSTRASSE 17 20095 Hamburg See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Hamburg Hamburg Hamburg Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 733 796,25 PANEPISTIMIO IOANNINON Greece Net EU contribution € 603 275,00 Address PANEPISTEMIOYPOLE PANEPISTEMIO IOANNINON 45110 Ioannina See on map Region Βόρεια Ελλάδα Ήπειρος Ιωάννινα Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 603 275,00