The main purpose of this study was to explore the health-promoting lifestyles and compare the diversity between the different background variables influenced health concept, perceived health status and health-promoting lifestyles among the college nurses. And this paper attempt to discuss the relationships between different background variables, health concept, health-promoting lifestyles, perceived health status and predictors of lifestyles. The study adopted questionnaire investigation and the adopted instruments were health-promoting lifestyle profile, health concept scale, perceived health status scale and demographic data. The subjects were the college nurses in Taiwan. A random sampling was adopted and data were collected from 170 school nurses. The effective questionnaire were 150 representing a 88.2 % of response rate, The data were analyzed by using mean, standard deviation, t-test, one way ANOVA, Pearson's product- moment correlation and multiple regression. The main conclusions of the study are as follows: 1. Most college nurses have the middle-upper positive health concept. In all aspects of health concept, the highest score was adapted health concept, and the lowest was the peaceful benedictional health concept. 2. In the perceived of health status, most college nurses considered their health status being normal or good. 3. The aspect of health-promoting lifestyles of the college nurses is good. The highest score was nutrition, and the lowest was exercise. 4. There were obviously positive relationships between some aspects of health concept and health-promoting lifestyles in the investigation of the college nurses. 5. There were obviously positive relationships between all aspects of perceived health status and health-promoting lifestyles in the investigation of the college nurses. 6. In the investigation of the college nurses, the perceived health status, participating the lessons of health-promoting lifestyles, and the seniority of school nurses working were the significant predictors and explained 21% of the variance of health-promoting lifestyles. However, perceived health status was the strongest predictor. According to the findings of this study could present as references for school health practice and administration to promote health-promoting lifestyles among the college school nurses and for further research in this field.