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    I. S. Lembryk, O. V. Zhyliak, O. O. Tsytsyura, I. V. Shlimkevych, O. V. Dutchuk, P. Z. Buyak, A. B. Stefanyshyn

    SOME INDICES OF METABOLISM IN CHILDREN WITH IRRITABLE BOWEL SYNDROME AND CO-EXISTING OVERWEIGHT


    About the author: I. S. Lembryk, O. V. Zhyliak, O. O. Tsytsyura, I. V. Shlimkevych, O. V. Dutchuk, P. Z. Buyak, A. B. Stefanyshyn
    Heading CLINICAL MEDICINE
    Type of article Scentific article
    Annotation In this article, we demonstrate the data on clinical course features of irritable bowel syndrome in children of school age with normal weight as well as co-existing overweight. Also, we conducted an assessment of certain indices of lipid and carbohydrate metabolism in these conditions. Clinical features of irritable bowel syndrome with overweight include duration of the disease (6.5±0.5 months), female sex (30 vs. 5 children, χ2=5.1429, p<0.05), abdominal pain syndrome (85 % vs. 65 %, p<0.05), intermittent diarrhoea and constipation (62.5 % vs. 90 %, p<0.05), and bloating (77.5 % vs. 50 %, p<0.05). Initial signs of impaired carbohydrate metabolism were detected: an increase in the level of C-peptide (4.5±0.01 and 2.5±0.03, p<0.05) and NOMA index (3.41±0.02 and 2.86±0.01, p<0.05). The given data indicate deviations from the norm of the evaluated indicators of certain types of metabolism in school-age children with irritable bowel syndrome and overweight that will be reversible in case of adequate therapy.
    Tags children,irritable bowel syndrome,overweight,faecal calprotectin
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    Publication of the article «World of Medicine and Biology» №4(86), 2023 year, 097-101 pages, index UDK 612.015.3+616.34+616.056.52+613.95
    DOI 10.26724/2079-8334-2023-4-86-97-101