SéminaireDépistage des patients déficitaires en dihydropyrimidine déhydrogénase avant traitement par fluoropyrimidines
Références (20)
- et al.
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial
Lancet
(2000) - et al.
An accurate Dihydrouracil/Uracil determination using improved High Performance Liquid Chromatography method for preventing fluoropyrimidines-related toxicity in clinical practice
J Chromatogr B
(2005) - et al.
Identification of a novel mutation in the dihydropyrimidine dehydrogenase gene in a patient with lethal outcome after 5-fluorouracil administration and determination of its frequency in a population of 500 patients with colorectal carcinoma
Clin Biochem
(2007) - et al.
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
J Clin Oncol
(2000) - et al.
Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity
New Engl J Med
(1985) - et al.
Dihydropyrimidine dehydrogenase: its role in 5-Fluorouracil clinical toxicity and tumor resistance
Clin Can. Res
(1999) - et al.
Population study of dihydropyrimidine dehydrogenase in cancer patients
J Clin Oncol
(1994) - et al.
Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients, and clinical implication in -fluorouracil chemotherapy
Cancer Res
(1993) - et al.
Familial deficiency of dihydropyrimidine dehydrogenase (biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity)
J Clin Invest
(1988) - et al.
Life-threatening toxicity in a dihydropyrimidine dehydrogenase deficient patient after treatment with topical 5-Fluorouracil
Clin Canc Res
(1999)
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