The aim of this study was to analyze the effects of different resistance exercise orders on training intensity in middle-aged and older women. Twenty-three participants (age 50-78 years) were randomized into two RT groups: One group started training sessions performing multi-joint exercises followed by single-joint exercises (MS, n = 12; 58.92 ± 5.53 years), while the other group performed their session in the opposite order (SM, n = 11; 57.93 ± 11.89 years). Both groups completed RT sessions ...

Precision nutrition requires the discovery and understanding of quantitative biomarkers with sufficient between person variability. In healthy individuals, glucose is used as the preferential energy substrate and is not readily stored. Circumstances such as disease, fasting, or injury, can cause glucose to be unable to be used or not readily available. In these circumstances the body can utilize alternative energy sources such as ketones derived from stored fatty acids....

Extracellular vesicles (EV) are small membrane bound vesicles which are capable of delivering biomolecules to neighbouring recipient cells or more distant cells, where they induce various signalling cascades and subsequently alter their metabolism. These EVs may include apoptotic bodies, microvesicles, and exosomes, which have emerged as important mediators of cell to cell communication in normal physiology and pathological status. ...