ORIGINAL ARTICLE   

Il Giornale Italiano di Radiologia Medica 2019 Settembre-Ottobre;6(5):443-53

DOI: 10.23736/S2283-8376.19.00192-X

Copyright © 2019 EDIZIONI MINERVA MEDICA

language: English, Italian

Magnetic resonance imaging in preoperative staging of gastric cancer: initial experience

Valeria MOLINELLI ¹ ✉, Nicola TARALLO ¹, Andrea COPPOLA ¹, Maria G. ANGERETTI ¹, Valeria BETTONI ¹, Valentina TROVAMALA ¹, Valeria QUINTODEI ², Mattia BERSELLI ³, Eugenio A. GENOVESE ¹

¹ Unit of Radiology and Imaging, University of Insubria, Varese, Italy; ² Unit of General Surgery, Civil Hospital of Legnano, Legnano, Milan, Italy; ³ Unit of Oncologic Surgery, Department of General Surgery, University of Insubria, Varese, Italy

BACKGROUND: The aim of the present study is to present an initial experience in the clinical value of magnetic resonance imaging (MRI) in the preoperative T staging of gastric cancer.
METHODS: In total, 15 patients with gastric cancer were investigated between September 2017 and September 2018. All patients underwent abdomen MRI with T2 weighted sequences (on axial, coronal and parasagittal planes), diffusion-weighted imaging sequences and axial gadolinium fat suppressed T1 weighted sequences, after the oral administration of 1 L of jellify water, obtained by mixing water and food thickener. The results of the MRI T staging (cT and cN) were compared to postoperative pathological diagnosis (pT and pN), according to the VIII edition of tumor-node-metastasis by AJCC.
RESULTS: Seven patients out of 15 patients underwent gastric surgery. The MRI localization of gastric cancer were confirmed by the histopathological exam after surgery in all case, even in case of pT1 tumors. In 3/7 cases a concordance was obtained between the cT and the pT, while in the remaining 3/7 cases MRI slightly overestimated the real T and in 1/7 cases the histological examination revealed the presence of a gastrointestinal stromal tumors. Regarding the N agreement, this was found in only 2/7 cases. Of the unoperated patients, 6/8 patients had a cT3 cN2 cM0, 1/8 cT3 cN2 cM1 (hepatic) and 1/8 cT4a cN2 cM0 radiological stage. All unoperated patients underwent neo-adjuvant therapy, with the exception of one patient who died shortly after the diagnosis.
CONCLUSIONS: The results were encouraging. In particular, with reference to pathological diagnosis, the MRI method could be a useful preoperative assessment. However, in order to obtain results of greater scientific evidence, it is our intention to expand the sample under examination and compare the MRI data with those of computed tomography.

KEY WORDS: Diagnostic imaging; Magnetic resonance imaging; Stomach neoplasms