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  • Abstract
  • CASE REPORT
  • DISCUSSION
  • CONCLUSION
  • REFERENCES
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Abstract

Dapsone is a leprostatic agent commonly prescribed for the management of leprosy, malaria, and the immunosuppression-induced infections of Pneumocystis carinii and Toxoplasma gondii. In susceptible patients, methemoglobinemia, a potentially life-threatening event, can occur. We report a case of dapsone-induced methemoglobinemia which was observed during general anesthesia for the management of a fractured mandible. The pathophysiology, diagnosis, and management of dapsone-induced methemoglobinemia will be discussed.

Keywords: Dapsone; Methemoglobinemia; Methemoglobin; Cyanosis; Glucose-6-phosphate dehydrogenase deficiency; Cytochrome b5 reductase; Acquired methemoglobinemia; Congenital methemoglobinemia
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Copyright: © 2007 American Dental Society of Anesthesiology
Citations

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Article Contents

Comparison of Remimazolam and Propofol for Intubated General Anesthesia for Oral and Maxillofacial Surgery

Yoshio Hayakawa DDS, PhD,
 Keiko Fujii-Abe DDS, PhD,
 Sayaka Akitomi DDS,
 Shihomi Niwa DDS,
 Michiru Abe DDS,
 Manami Otsuka DDS, PhD,
 Maho Ikeda DDS,
 Takumi Ishikawa DDS, PhD,
 Manami Yajima DDS, PhD, and
 Hiroshi Kawahara DDS, PhD

The Impact of COVID-19 on Dental Anesthesiologists: An Online Survey of Board-Certified Dental Anesthesiology Specialists of the Japanese Dental Society of Anesthesiology

Takuro Sanuki DDS, PhD,
 Hidetaka Kuroda DDS, PhD,
 Uno Imaizumi DDS, PhD,
 Shota Tsukimoto DDS, PhD,
 Norika Katagiri DDS, PhD,
 Ayako Mizutani DDS, PhD,
 Mari Ohnaka DDS,
 Shinji Kurata DDS, PhD,
 Naotaka Kishimoto DDS, PhD, and
 Kanta Kido DDS, PhD

Tracheal Bronchus Detected During General Anesthesia: A Case Report

Toru Yamamoto DDS, PhD,
 Tatsuru Tsurumaki DDS, PhD,
 Hiroko Kanemaru DDS, PhD, and
 Kenji Seo DDS, PhD

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Tiffany Smith BS,
 Rachel Blum BS, and
 Raquel Rozdolski DMD
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