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Ni(II), Pd(II) and Pt(II) complexes with ligand containing thiosemicarbazone and semicarbazone moiety: Synthesis, characterization and biological investigation

Chandra Sulekh (Department of Chemistry, Zakir Husain College, New Delhi, India)
Tyagi Monika (Department of Chemistry, Zakir Husain College, New Delhi, India)

The synthesis of nickel(II), palladium(II) and platinum(II) complexes with thiosemicarbazone and semicarbazone of p-tolualdehyde are reported. All the new compounds were characterized by elemental analysis, molar conductance measurements, magnetic susceptibility measurements, mass, 1H-NMR, IR and electronic spectral studies. Based on the molar conductance measurements in DMSO, the complexes may be formulated as [Ni(L)2Cl2] and [M(L)2]Cl2 (where M = Pd(II) and Pt(II)) due to their non-electrolytic and 1:2 electrolytic nature, respectively. The spectral data are consistent with an octahedral geometry around Ni(II) and a square planar geometry for Pd(II) and Pt(II), in which the ligands act as bidentate chelating agents, coordinated through the nitrogen and sulphur/oxygen atoms. The ligands and their metal complexes were screened in vitro against fungal species Alternaria alternata, Aspergillus niger and Fusarium odum, using the food poison technique. .

Keywords: thiosemicarbazone, semicarbazone, transition metal complexes, spectral studies, biological screening