Nuclear Technology and Radiation Protection 2014 Volume 29, Issue 1, Pages: 28-33
https://doi.org/10.2298/NTRP1401028F
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A new approach to targetry and cyclotron production of 45Ti by proton irradiation of 45Sc
Fazaeli Yousef (Nuclear Medicine Research Group, Agricultural, Medical and Industrial Research School, Karaj, Iran)
Aboudzadeh Mohammadreza (Nuclear Medicine Research Group, Agricultural, Medical and Industrial Research School, Karaj, Iran)
Aardaneh Khosro (Nuclear Medicine Research Group, Agricultural, Medical and Industrial Research School, Karaj, Iran)
Kakavand Tayyeb (Faculty of Physics, Zanjan University, Zanjan, Iran)
Bayat Fatemeh (Faculty of Physics, Zanjan University, Zanjan, Iran)
Yousefi Kamran (Nuclear Medicine Research Group, Agricultural, Medical and Industrial Research School, Karaj, Iran)
Titanium-45 with a half-life of 3.09 hours decays by emission of positrons
(85%) and the electron capture process (15%). These properties make this
radionuclide useful in the diagnosis of tumors by positron emission
tomography. In this study, after having considered the excitation functions
for the 45Sc(p, n)45Ti reaction using TALYS and ALICE/ASH codes and after the
comparison with other experimental data, 45Ti was produced by dint of the
pressing method and a newly designed and manufactured shuttle and capsule,
resulting in an experimental yield of 403.3 MBq/mAh. Essential target
thickness and physical yield were calculated. The scandium oxide target was
irradiated at a 20 mA current and a 21 MeV proton beam energy for 1 hour.
Keywords: 45Ti, 45Sc, proton, excitation function, physical yield