Journal of the Serbian Chemical Society 2008 Volume 73, Issue 10, Pages: 961-965
https://doi.org/10.2298/JSC0810961G
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Antifungal activity of Nepeta rtanjensis essential oil
Grbić-Ljaljević Milica (Institut za botaniku i Botanička bašta 'Jevremovac', Biološki fakultet, Beograd)
Stupar Miloš 
(Institut za botaniku i Botanička bašta 'Jevremovac', Biološki fakultet, Beograd)
Vukojević Jelena (Institut za botaniku i Botanička bašta 'Jevremovac', Biološki fakultet, Beograd)
Soković Marina (Institute for Biological Research "Siniša Stanković", Belgrade)
Mišić Danijela (Institut za biološka istraživanja 'Siniša Stanković', Beograd)
Grubišić Dragoljub (Institut za biološka istraživanja 'Siniša Stanković', Beograd)
Ristić Mihailo (Institut za proučavanje lekovitog bilja 'dr. Josif Pančić', Beograd)
The chemical composition and antifungal activity of the essential oil of an endemic Serbian plant Nepeta rtanjensis Diklić & Milojević was studied. The essential oil was isolated from cultivated plants. Inhibition of mycelia growth of five micromycetes, two Alternaria species originally isolated from N. rtanjensis, Cladosporium cladosporoides, Trichoderma viride and Bipolaris spicifera, were tested using the agar dilution method. The essential oil of N. rtanjensis, the main component of which was 4aa,7a,7ab-nepetalactone, showed strong antifungal activity against all the tested micromycetes. The minimum inhibitory concentration of N. rtanjensis essential oil ranged from 0.6 to 1.4 μg mL-1. The fungi most sensitive to the tested oil were Alternaria species, while Trichoderma viride was the most resistant.
Keywords: Nepeta rtanjensis, essential oil, antifungal activity