Archives of Biological Sciences 2013 Volume 65, Issue 2, Pages: 571-576
https://doi.org/10.2298/ABS1302571S
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Fractional flow reserve of intermediate lesions on collateral donor coronary arteries after myocardial infarction
Simić I. (Faculty of Medical Sciences, Kragujevac + Clinic for Cardiology, Clinical Center Kragujevac, Kragujevac)
Zdravković V. (Faculty of Medical Sciences, Kragujevac + Clinic for Cardiology, Clinical Center Kragujevac, Kragujevac)
Davidović G. (Faculty of Medical Sciences, Kragujevac + Clinic for Cardiology, Clinical Center Kragujevac, Kragujevac)
Irić-Ćupić Violeta (Faculty of Medical Sciences, Kragujevac + Clinic for Cardiology, Clinical Center Kragujevac, Kragujevac)
Vučić Rada 
(Faculty of Medical Sciences, Kragujevac + Clinic for Cardiology, Clinical Center Kragujevac, Kragujevac)
Tasić M. (Clinic for Cardiology, Clinical Center Kragujevac, Kragujevac)
Ignjatović V. (Clinic for Cardiology, Clinical Center Kragujevac, Kragujevac)
Fractional flow reserve (FFR) is the gold standard for the functional
assessment of coronary arteries. The aim of this study was to evaluate the
relation between angiography, QCA and FFR in borderline lesions on collateral
donor coronary arteries. In addition, FFR is compared with the angiographic
appearance of collaterals to infarction-related arteries and
echocardiographically assessed viability of infarct related the LV wall. In
60 patients with previous IM and occluded IRA, functional assessment of
borderline coronary stenosis (30-70% DS) on collaterals donor artery was
performed. We have not found statistically significant differences in these
parameters between groups with different angiographic appearances of
collaterals and different viability of distal myocardium. However, we found
higher FFR values in diabetic patients (p=0.018). Higher FFR values in
diabetic patients reveal the negative effects of diabetes on collateral
growth and myocardial viability.
Keywords: FFR, collaterals, intermediate stenosis, diabetes mellitus