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Clinical utility of N-acetylcysteine in important liver toxicity following high-dose chemotherapy and autologous stem cell transplantation. Single center experience
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  • Uros Markovic,
  • Paola Scire,
  • Gabriella Amato,
  • Federica Galbo,
  • Giulio Antonio Milone,
  • Gaetano Moschetti
Uros Markovic
Mediterranean Oncology Institute

Corresponding Author:[email protected]

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Paola Scire
Mediterranean Oncology Institute
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Gabriella Amato
Mediterranean Oncology Institute
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Federica Galbo
Mediterranean Oncology Institute
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Giulio Antonio Milone
Mediterranean Oncology Institute
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Gaetano Moschetti
Mediterranean Oncology Institute
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Abstract

Chemotherapy-induced hepatic toxicity is a frequent problem, with some patients developing liver failure. Unfortunately, therapeutic possibilities are still lacking. Here, we describe two patients that developed important liver toxicity in our center following high-dose chemotherapy and were successfully treated with high-dose N-acetylcysteine.