Clinical utility of N-acetylcysteine in important liver toxicity
following high-dose chemotherapy and autologous stem cell
transplantation. Single center experience
- Uros Markovic,
- Paola Scire,
- Gabriella Amato,
- Federica Galbo,
- Giulio Antonio Milone,
- Gaetano Moschetti
Abstract
Chemotherapy-induced hepatic toxicity is a frequent problem, with some
patients developing liver failure. Unfortunately, therapeutic
possibilities are still lacking. Here, we describe two patients that
developed important liver toxicity in our center following high-dose
chemotherapy and were successfully treated with high-dose
N-acetylcysteine.