An Investigation and Analysis of Features of ( Codonopsis javanica (Blume) Hook.F & Thoms) in SON LA

— Codonopsis Javanica (Blume) Hook.F & Thoms is called with Scientific name: Codonopsis javanica (Blume) Hook.f. & Thomson, Campanulaceae (the bellflower family).Plant description: Herbaceous, perennial, creeping by winding stems. Body pale green or purple. Leaves opposite, rarely staggered, heart-shaped at base, pointed at tip; edges are wavy or slightly notched. Roots cylindrical long, diameter can reach 1.5-2 cm, branched, root tips enlarged, with many keloid scars. Flowers grow individually in the interstitium, bell-shaped, white or yellowish, with purple veins in the throat. Fruit capsule, globose with 5 translucent edges, purple or red-purple when ripe, many seeds. The whole plant has white latex. Harvest in winter, wash the soil, cut off the roots and rootlets, dry in the sun or dry at low temperature to slightly dry, roll until soft, then gently dry again. In the paper authors also mentuiond its uses and usage: Ginseng is used to treat depression, anorexia, fatigue, anemia; also used in uterine prolapse, haemorrhage, haemorrhage, jaundice, leukocytosis, nephritis, albumin urine... Used alone or in combination with other drugs.. Codonopsis Javanica (Blume) from Codonopsis javanica Hook. f. et Thomson using hot water extraction method, which was separated and purified by DEAE-cellulose column and Sepharose CL-6B column. The structure of the purified component was preliminary characterized by gas chromatography-mass spectrometer (GC-MS), high performance gel permeation chromatography (HPGPC) and infrared spectroscopy (IR). By examining the degree of delayed-type hypersensitivity (DTH) in mice and carbon particle clearance index, the immunomodulatory activity was clarified. The results showed that the extraction rate of CJP was 24.9 ± 0.5%. After purification, the refined polysaccharides component (CJP-2) was obtained. The structural characterization results indicated that CJP-2 was mainly composed of mannose, glucose, and galactose, and its molecular weight was 790 Da. Immunomodulation results showed that the low and medium levels of CJP significantly enhanced the degree of DTH in mice (P < 0.05). CJP can improve the clearance index of mice and enhance their charcoal removal function. The study indicates that C. javanica is a good source of polysaccharides, and CJP may be a new type of immunomodulator.


INTRODUCTION
Codonopsis Javanica is called Dang sam (Vietnamese), kind of ginseng is the dried or dried root of the ginseng plant (Codolopsis sp), the bell flower family (Campanulaceae). It is ginseng in Vietnam [Codolopsis javanica (Blume) Hook f.] has the same chemical composition and uses as other ginsengs. The tree grows wild and is grown in some highlands. Pharmaceutical materials must be partly imported from China.

II. PREVIOUS STUDIES
We analyze in below table: Wu et al 2020 the crude polysaccharides of C. javanica (CJP) was obtained from Codonopsis javanica (Blume) Hook. f. et Thomson using hot water extraction method, which was separated and purified by DEAE-cellulose column and Sepharose CL-6B column. The structure of the purified component was preliminary characterized by gas chromatography-mass spectrometer (GC-MS), high performance gel permeation chromatography (HPGPC) and infrared spectroscopy (IR). By examining the degree of delayed-type hypersensitivity (DTH) in mice and carbon particle clearance index, the immunomodulatory activity was clarified. The results showed that the extraction rate of CJP was 24.9 ± 0.5%. After purification, the refined polysaccharides component (CJP-2) was obtained. The structural characterization results indicated that CJP-2 was mainly composed of mannose, glucose, and galactose, and its molecular weight was 790 Da. Immunomodulation results showed that the low and medium levels of CJP significantly enhanced the degree of DTH in mice (P < 0.05). CJP can improve the clearance index of mice and enhance their charcoal removal function. The study indicates that C. javanica is a good source of polysaccharides, and CJP may be a new type of immunomodulator.
Codonopsis Javanica is used as a tonic to treat diseases related to raw, loose or broken stools, indigestion, pale face, low voice, weak limbs, shortness of breath, fatigue, and waste. In addition, iso ginseng is also used instead of ginseng in remedies that can treat diseases such as weak digestion, poor digestion, along with other medicines such as Bach Truc, Bach Linh, Hoai Son, Lien humiliation (source: author synthesis)

III. METHODOLOGY
Authors collect A wide range of data for analyses and propose solutions. Observations in Vietnam planting were also mentioned. Then, Interviews were conducted on the basis of simple questionnaires stating a number of key questions to meet the content objectives of the research. The interview process was conducted flexibly, and local languages were used to facilitate collection information.  (2007) under the VU level (will be endangered), group 2 in the List of endangered and rare forest plants and animals in the Decree 06/2019 of the Government of Vietnam. Research results have clarified the characteristics of natural forests where species are distributed in terms of forest nests, mother trees, regenerated trees, demand for use, market for consumption, and methods of collection by local people. Codonopsis Javanica (Blume) Hook.F & Thoms root is a product very familiar to the local community in Son La from generations to now. In the community of people living near the forest (mainly the Thai community, the H'Mong people) have passed on the experience of species identification, how to exploit, use, and begin to pay attention to planting in the garden. households and commercialization of products. These are important bases for breeding and afforestation to develop this species locally.

Planting
We look at below chart:   Nguyen Thi Bich Ngoc (2022) mentioned Van Ho district, Son La province has long recorded the natural distribution and is the place to exchange and trade many medicinal species, including C. javanica. The roots of C. javanica, which are collected in the wild, especially under the forest canopy, are very clean and healthy organic products that are popular with consumers. Together with the sharing from the community about the experience in using C. javanica products for health care, this product has become even more attractive. Population with a specificity, up to 85% are Percentage of yes (%)