Endoscopic Endonasal Dural Reconstruction for a Cerebrospinal Fluid Leak in the Middle Cranial Fossa of a Patient with Gorham-stout Disease with Skull Base Defect

Yusuke MORINAGA; Hiroyoshi AKUTSU; Hiroyoshi KINO; Shuho TANAKA; Hidetaka MIYAMOTO; Masahide MATSUDA; Eiichi ISHIKAWA

doi:10.2176/jns-nmc.2021-0319

CASE REPORT

Endoscopic Endonasal Dural Reconstruction for a Cerebrospinal Fluid Leak in the Middle Cranial Fossa of a Patient with Gorham-stout Disease with Skull Base Defect

Yusuke MORINAGA, Hiroyoshi AKUTSU, Hiroyoshi KINO, Shuho TANAKA, Hidetaka MIYAMOTO, Masahide MATSUDA, Eiichi ISHIKAWA

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Keywords: Gorham-Stout disease, cerebrospinal fluid leak, endoscopic endonasal surgery, dural reconstruction, skull base

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Supplementary material

2022 Volume 9 Pages 55-61

DOI https://doi.org/10.2176/jns-nmc.2021-0319

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Abstract

We report the use of endoscopic endonasal surgery for dural reconstruction following a cerebrospinal fluid leak in a 33-year-old patient with recurrent meningitis since at age of 2 years. Magnetic resonance imaging showed osteolytic changes in the left temporal and sphenoid bones, including the left pterygoid plate, a few left temporal encephaloceles, and cerebrospinal fluid-like fluid in the expanded Meckel's cave and the parapharyngeal space. After endoscopic endonasal surgery, Gorham-Stout disease was diagnosed. No recurrence of cerebrospinal fluid leakage or meningitis has been observed. Thus, endoscopic endonasal surgery might improve clinical outcomes in patients with Gorham-Stout disease and skull base defects.

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