Abstract
Ayurveda captured almost all herbs in its indications for therapeutics from the period of Vedas. More than 700 plants are discussed elaborately in various classics of Ayurveda of different periods. Berberis aristata DC (Berberidaceae), an Indian medicinal plant, is an Ayurvedic herb used since ancient times. It is commonly known as Daruharidra and Daruhaldi. The plant is useful as an antipyretic, antibacterial, antimicrobial, antihepatotoxic, anti-diabetic, anticancer, antioxidant, and hypolipidemic agent. Our main objective was to collect information about the active constituents and major pharmacological actions of B. aristata. The review of the literature included PubMed and Science Direct searches with ‘Berberis aristata’ and ‘Daruharidra’ as initial keywords. This review aims to highlight the ethnomedicinal and pharmacological uses of B. aristata, which will give insights into developing potentially new bioactives from the plant scaffolds. This review also highlights the phytochemicals isolated from different parts of B. aristata. Daruharidra is a rich source of chemically novel compounds, such as berberine, and needs elaborate screening strategies to dwell into the pharmacological effects at the molecular level.
Keywords: Berberis aristata, Berberine, Berberidaceae, Phytochemistry, Pharmacology.
Current Traditional Medicine
Title:A Critical Review on the Unexplored Therapeutic Treasure of Himalayan Ayurvedic Drug Daruharidra (Berberis Aristata)
Volume: 7 Issue: 3
Author(s): Javed Ahamad*, Raad A Kaskoos, Faraat Ali and Showkat R. Mir
Affiliation:
- Department of Pharmacognosy, Faculty of Pharmacy, Tishk International University, Erbil, Kurdistan Region,Iraq
Keywords: Berberis aristata, Berberine, Berberidaceae, Phytochemistry, Pharmacology.
Abstract: Ayurveda captured almost all herbs in its indications for therapeutics from the period of Vedas. More than 700 plants are discussed elaborately in various classics of Ayurveda of different periods. Berberis aristata DC (Berberidaceae), an Indian medicinal plant, is an Ayurvedic herb used since ancient times. It is commonly known as Daruharidra and Daruhaldi. The plant is useful as an antipyretic, antibacterial, antimicrobial, antihepatotoxic, anti-diabetic, anticancer, antioxidant, and hypolipidemic agent. Our main objective was to collect information about the active constituents and major pharmacological actions of B. aristata. The review of the literature included PubMed and Science Direct searches with ‘Berberis aristata’ and ‘Daruharidra’ as initial keywords. This review aims to highlight the ethnomedicinal and pharmacological uses of B. aristata, which will give insights into developing potentially new bioactives from the plant scaffolds. This review also highlights the phytochemicals isolated from different parts of B. aristata. Daruharidra is a rich source of chemically novel compounds, such as berberine, and needs elaborate screening strategies to dwell into the pharmacological effects at the molecular level.
Export Options
About this article
Cite this article as:
Ahamad Javed *, Kaskoos A Raad , Ali Faraat and Mir R. Showkat , A Critical Review on the Unexplored Therapeutic Treasure of Himalayan Ayurvedic Drug Daruharidra (Berberis Aristata), Current Traditional Medicine 2021; 7 (3) . https://dx.doi.org/10.2174/2215083806999201117160106
DOI https://dx.doi.org/10.2174/2215083806999201117160106 |
Print ISSN 2215-0838 |
Publisher Name Bentham Science Publisher |
Online ISSN 2215-0846 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Management of Hemorrhoidal Disease in Special Conditions: A Word of Caution
Reviews on Recent Clinical Trials Review of Medicinal Plants Common to Traditional Chinese and Indian Medicines with Relevance to Non-Communicable Diseases
Current Traditional Medicine Extraction and Evaluation of Anti-inflammatory and Analgesic Activity of Mimosa rubicaulis in Swiss Albino Rats
Anti-Infective Agents Anti-Inflammatory Effects of Triterpenoids; Naturally Occurring and Synthetic Agents
Mini-Reviews in Organic Chemistry Idronoxil as an Anticancer Agent: Activity and Mechanisms
Current Cancer Drug Targets The Management of Acute Hemorrhoidal Disease
Reviews on Recent Clinical Trials Synthesis of Rutin Derivatives to Enhance Lipid Solubility and Development of Topical Formulation with a Validated Analytical Method
Current Drug Delivery Global Gastrointestinal Safety Profile of Etoricoxib and Lumiracoxib
Current Pharmaceutical Design Malignancy in Common Variable Immune Deficiency: Report of Two Rare Cases of Gastrointestinal Malignancy and a Review of the Literature
Cardiovascular & Hematological Disorders-Drug Targets Signs and Related Mechanisms of Ethanol Hepatotoxicity
Current Drug Abuse Reviews Distribution, Bioactivities and Therapeutical Potentials of Pentagalloylglucopyranose
Current Bioactive Compounds Endogenous and Exogenous Ligands of Aryl Hydrocarbon Receptor: Current State of Art
Current Drug Metabolism Refractory Cough as a Remote Manifestation of Retroperitoneal Liposarcoma
Current Cancer Therapy Reviews Identification of Novel Anti-inflammatory Agents from Ayurvedic Medicine for Prevention of Chronic Diseases: “Reverse Pharmacology” and “Bedside to Bench” Approach
Current Drug Targets Postoperative Complications in Hemorrhoidal Disease and Special Conditions
Reviews on Recent Clinical Trials Safety and Efficacy of Proctosoll Allevia in the Management of Haemorrhoidal Disease in Adults: A Prospective Randomized Clinical Trial
Reviews on Recent Clinical Trials Chemical and Biological Aspects of the Genus Verbesina
The Natural Products Journal Mediterranean Cypress “Cupressus sempervirens”: A Review on Phytochemical and Pharmacological Properties
Current Traditional Medicine Post-Hemorrhoidectomy Pain Management: The Latest News
Reviews on Recent Clinical Trials Hemorrhoidal Laser Procedure (HeLP) and Hemorrhoidal Laser Procedure + Mucopexy (HeLPexx) and Other Emerging Technologies
Reviews on Recent Clinical Trials