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Infectious Disorders - Drug Targets

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ISSN (Print): 1871-5265
ISSN (Online): 2212-3989

Systematic Review Article

The Effectiveness of Face Masks in Preventing COVID-19 Transmission: A Systematic Review

Author(s): SeyedAhmad SeyedAlinaghi, Amirali Karimi*, Amir Masoud Afsahi, Pegah Mirzapour, Sanaz Varshochi, Hengameh Mojdeganlou, Paniz Mojdeganlou, Armin Razi, Sanam Alilou, Mohsen Dashti, Afsaneh Ghasemzadeh, Solmaz Saeidi, Esmaeil Mehraeen* and Omid Dadras

Volume 23, Issue 8, 2023

Published on: 03 August, 2023

Article ID: e010623217509 Pages: 11

DOI: 10.2174/1871526523666230601090905

Price: $65

Abstract

Introduction: Since the beginning of the COVID-19 pandemic, face masks have been among the cornerstones of COVID-19 prevention. Therefore, evaluating their preventive effects against COVID-19 is crucial. This review aimed to systematically search for the systematic review articles that explored the role of various types of face masks in preventing COVID-19.

Methods: We browsed the keywords of this study in the online databases of Scopus, Web of Science, PubMed, and Cochrane on 10th January 2023 and retrieved all the relevant systematic review articles. The records were downloaded into an Endnote file, and the duplicates were removed. A two-step screening process consisting of title/abstract and full-text screenings was conducted to select the most relevant articles. To ensure the validity and reliability of the results, this study adhered to the PRISMA protocol.

Results: A total of 28 systematic reviews were included in this review. Most studies found that face masks are beneficial against viral respiratory infections, such as COVID-19. Different types of masks were evaluated in included studies. It appeared that mask efficacy depends on the material, layers, fitting on the face and user compliance. N 95 respirator had maximum efficacy, especially when used continuously.

Conclusion: Face masks have a beneficial effect against COVID-19. Home masks are less protective than surgical masks or N95 personal breathing masks. Besides, the use of masks may elicit a false sense of security in people, which may lead to poor hand hygiene and violation of social distancing. Therefore, the necessary training should be provided to the public to increase awareness and encourage the right practice of using the mask, emphasizing the preventive effects of washing hands, social distancing, and using a face mask against COVID-19.

Keywords: Cloth mask, COVID-19, face mask, mask, n-95, SARS-CoV-2, surgical mask.

Graphical Abstract
[1]
Mehraeen E, Salehi MA, Behnezhad F, Moghaddam HR. SeyedAlinaghi S. Transmission modes of COVID-19: A systematic review. Infect Disord Drug Targets 2021; 21(6): e170721187995.
[http://dx.doi.org/10.2174/1871526520666201116095934] [PMID: 33200716]
[2]
SeyedAlinaghi S, Karimi A, Mohsseni Pour M, et al. The clinical outcomes of COVID-19 in HIV-positive patients: A systematic review of current evidence. Immun Inflamm Dis 2021; 9(4): 1160-85.
[http://dx.doi.org/10.1002/iid3.497] [PMID: 34324280]
[3]
Karimi A, Nowroozi A, Alilou S, Amini E. Effects of androgen deprivation therapy on COVID-19 in patients with prostate cancer: A systematic review and meta-analysis. Urol J 2021; 18(6): 577-84.
[PMID: 34302737]
[4]
WHO. Coronavirus (COVID-19) Dashboard, The World Health Organization. 2022. Available from: https://covid19.who.int/
[5]
Oliaei S. SeyedAlinaghi S, Mehrtak M, et al. The effects of hyperbaric oxygen therapy (HBOT) on coronavirus disease-2019 (COVID-19): A systematic review. Eur J Med Res 2021; 26(1): 96.
[http://dx.doi.org/10.1186/s40001-021-00570-2] [PMID: 34412709]
[6]
Mehraeen E, Dadras O, Afsahi AM, et al. Vaccines for COVID-19: A systematic review of feasibility and effectiveness. Infect Disord Drug Targets 2022; 22(2): e230921196758.
[http://dx.doi.org/10.2174/1871526521666210923144837] [PMID: 34554905]
[7]
SeyedAlinaghi S, Karimi A, Barzegary A, et al. Mucormycosis infection in patients with COVID-19: A systematic review. Health Sci Rep 2022; 5(2): e529.
[http://dx.doi.org/10.1002/hsr2.529] [PMID: 35252593]
[8]
Dadras O, Alinaghi SAS, Karimi A, et al. Effects of COVID-19 prevention procedures on other common infections: A systematic review. Eur J Med Res 2021; 26(1): 67.
[http://dx.doi.org/10.1186/s40001-021-00539-1] [PMID: 34217366]
[9]
Iboi E, Richardson A, Ruffin R, et al. Impact of public health education program on the novel coronavirus outbreak in the United States. Front Public Health 2021; 9: 630974.
[http://dx.doi.org/10.3389/fpubh.2021.630974] [PMID: 33791268]
[10]
Ray A, Aggarwal N, Dwarakanathan V, Gautam N. Facemasks for prevention of viral respiratory infections in community settings: A systematic review and meta-analysis. Indian J Public Health 2020; 64(6): 192.
[http://dx.doi.org/10.4103/ijph.IJPH_470_20] [PMID: 32496254]
[11]
Chowdhury MA, Shuvho MBA, Shahid MA, et al. Prospect of biobased antiviral face mask to limit the coronavirus outbreak. Environ Res 2021; 192: 110294.
[http://dx.doi.org/10.1016/j.envres.2020.110294] [PMID: 33022215]
[12]
CDC. Science brief: Community use of cloth masks to control the spread of SARS-CoV-2. 2020. Available from: cdc.gov/coronavirus/2019-ncov/science/science-briefs/masking-science-sars-cov2.html
[13]
Pan J, Harb C, Leng W, Marr LC. Inward and outward effectiveness of cloth masks, a surgical mask, and a face shield. Aerosol Sci Technol 2021; 55(6): 718-33.
[http://dx.doi.org/10.1080/02786826.2021.1890687]
[14]
Howard J, Huang A, Li Z, et al. An evidence review of face masks against COVID-19. Proc Natl Acad Sci 2021; 118(4): e2014564118.
[http://dx.doi.org/10.1073/pnas.2014564118] [PMID: 33431650]
[15]
Ataei M. Assessment of cloth masks ability to limit COVID-19 particles spread: A systematic review. Environ Sci Pollut Res Int 2021; 29(2): 1645-76.
[PMID: 34689269]
[16]
Coclite D, Napoletano A, Gianola S, et al. Face mask use in the community for reducing the spread of COVID-19: A systematic review. Front Med 2021; 7: 594269.
[http://dx.doi.org/10.3389/fmed.2020.594269] [PMID: 33511141]
[17]
Perski O, Szinay D, Corker E, et al. Interventions to increase personal protective behaviours to limit the spread of respiratory viruses: A rapid evidence review and meta-analysis. Br J Health Psychol 2022; 27(1): 215-64.
[http://dx.doi.org/10.1111/bjhp.12542]
[18]
Chu DK, Akl EA, Duda S, et al. Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: A systematic review and meta-analysis. Lancet 2020; 395(10242): 1973-87.
[http://dx.doi.org/10.1016/S0140-6736(20)31142-9] [PMID: 32497510]
[19]
Collins AP, Service BC, Gupta S, et al. N95 respirator and surgical mask effectiveness against respiratory viral illnesses in the healthcare setting: A systematic review and meta-analysis. J Am Coll Emerg Physicians Open 2021; 2(5): e12582.
[http://dx.doi.org/10.1002/emp2.12582] [PMID: 34746923]
[20]
Tian C, Lovrics O, Vaisman A, et al. Risk factors and protective measures for healthcare worker infection during highly infectious viral respiratory epidemics: A systematic review and meta-analysis. Infect Control Hosp Epidemiol 2021; 43(5): 639-50.
[PMID: 33487203]
[21]
Page MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. Int J Surg 2021; 88: 105906.
[http://dx.doi.org/10.1016/j.ijsu.2021.105906] [PMID: 33789826]
[22]
Bartoszko JJ, Farooqi MAM, Alhazzani W, Loeb M. Medical masks vs N95 respirators for preventing COVID-19 in healthcare workers: A systematic review and meta-analysis of randomized trials. Influenza Other Respir Viruses 2020; 14(4): 365-73.
[http://dx.doi.org/10.1111/irv.12745] [PMID: 32246890]
[23]
Camargo MC, Martinez-Silveira MS, Lima AA, et al. Effectiveness of the use of non-woven face mask to prevent coronavirus infections in the general population: A rapid systematic review. Cien Saude Colet 2020; 25(9): 3365-76.
[http://dx.doi.org/10.1590/1413-81232020259.13622020] [PMID: 32876275]
[24]
Chaabna K, Doraiswamy S, Mamtani R, Cheema S. Facemask use in community settings to prevent respiratory infection transmission: A rapid review and meta-analysis. Int J Infect Dis 2021; 104: 198-206.
[http://dx.doi.org/10.1016/j.ijid.2020.09.1434] [PMID: 32987183]
[25]
Chan VWS, Ng HHL, Rahman L, et al. Transmission of severe acute respiratory syndrome coronavirus 1 and severe acute respiratory syndrome coronavirus 2 during aerosol-generating procedures in critical care. Crit Care Med 2021; 49(7): 1159-68.
[http://dx.doi.org/10.1097/CCM.0000000000004965] [PMID: 33749225]
[26]
Ford N, Holmer HK, Chou R, et al. Mask use in community settings in the context of COVID-19: A systematic review of ecological data. EClinicalMedicine 2021; 38: 101024.
[http://dx.doi.org/10.1016/j.eclinm.2021.101024] [PMID: 34308320]
[27]
Fouladi Dehaghi B, Ghodrati-Torbati A, Teimori G, Ibrahimi Ghavamabadi L, Jamshidnezhad A. Face masks vs. COVID-19: A systematic review. Invest Educ Enferm 2020; 38(2): e13.
[http://dx.doi.org/10.17533/udea.iee.v38n2e13] [PMID: 33047556]
[28]
Khalil MI, Banik GR, Mansoor S, Alqahtani AS, Rashid H. SARS-CoV-2, surgeons and surgical masks. World J Clin Cases 2021; 9(10): 2170-80.
[http://dx.doi.org/10.12998/wjcc.v9.i10.2170] [PMID: 33869593]
[29]
Li Y, Liang M, Gao L, et al. Face masks to prevent transmission of COVID-19: A systematic review and meta-analysis. Am J Infect Control 2021; 49(7): 900-6.
[http://dx.doi.org/10.1016/j.ajic.2020.12.007] [PMID: 33347937]
[30]
Li Y, Wei Z, Zhang J, et al. Wearing masks to reduce the spread of respiratory viruses: A systematic evidence mapping. Ann Transl Med 2021; 9(9): 811.
[http://dx.doi.org/10.21037/atm-20-6745] [PMID: 34268424]
[31]
Liang M, Gao L, Cheng C, et al. Efficacy of face mask in preventing respiratory virus transmission: A systematic review and meta-analysis. Travel Med Infect Dis 2020; 36: 101751.
[http://dx.doi.org/10.1016/j.tmaid.2020.101751] [PMID: 32473312]
[32]
Locke L, Dada O, Shedd JS. Aerosol transmission of infectious disease and the efficacy of Personal Protective Equipment (PPE). J Occup Environ Med 2021; 63(11): e783-91.
[http://dx.doi.org/10.1097/JOM.0000000000002366] [PMID: 34419986]
[33]
MacIntyre CR, Chughtai AA. A rapid systematic review of the efficacy of face masks and respirators against coronaviruses and other respiratory transmissible viruses for the community, healthcare workers and sick patients. Int J Nurs Stud 2020; 108: 103629.
[http://dx.doi.org/10.1016/j.ijnurstu.2020.103629] [PMID: 32512240]
[34]
Nanda M, Sharma R. COVID-19: A comprehensive review of epidemiology and public health system response in nordic region. Int J Health Serv 2021; 51(3): 287-99.
[http://dx.doi.org/10.1177/0020731421994840] [PMID: 33656388]
[35]
Sharma S, Mishra M, Mudgal S. Efficacy of cloth face mask in prevention of novel coronavirus infection transmission: A systematic review and meta-analysis. J Educ Health Promot 2020; 9(1): 192.
[http://dx.doi.org/10.4103/jehp.jehp_533_20] [PMID: 33015206]
[36]
Tabatabaeizadeh SA. Airborne transmission of COVID-19 and the role of face mask to prevent it: A systematic review and meta-analysis. Eur J Med Res 2021; 26(1): 1.
[http://dx.doi.org/10.1186/s40001-020-00475-6] [PMID: 33388089]
[37]
Tran TQ, Mostafa EM, Tawfik GM, et al. Efficacy of face masks against respiratory infectious diseases: A systematic review and network analysis of randomized-controlled trials. J Breath Res 2021; 15(4): 047102.
[http://dx.doi.org/10.1088/1752-7163/ac1ea5] [PMID: 34407516]
[38]
Yin X, Wang X, Xu S, He C. Comparative efficacy of respiratory personal protective equipment against viral respiratory infectious diseases in healthcare workers: A network meta-analysis. Public Health 2021; 190: 82-8.
[http://dx.doi.org/10.1016/j.puhe.2020.11.004] [PMID: 33360295]
[39]
Crespo NC, Fornasier JM, Dionicio P, Godino JG, Ramers C, Elder J. Effectiveness of face masks in preventing COVID-19 transmission in real-world settings: A systematic literature review. Res Sq 2023.
[http://dx.doi.org/10.21203/rs.3.rs-2534269/v1]
[40]
Hajmohammadi M, Saki Malehi A, Maraghi E. Effectiveness of using face masks and personal protective equipment to reducing the spread of COVID-19: A systematic review and meta-analysis of case–control studies. Adv Biomed Res 2023; 12(1): 36.
[PMID: 37057222]
[41]
Majidi S, Feizi A, Hajizadeh Y. The effect of face mask, air temperature, and humidity on COVID-19 transmission: A systematic review and meta-analysis. Health Scope 2022; 11(4): e129121.
[http://dx.doi.org/10.5812/jhealthscope-129121]
[42]
Alihsan B, Mohammed A, Bisen Y, Lester J, Nouryan C, Cervia J. The efficacy of facemasks in the prevention of COVID-19: A systematic review. medRxiv 2022; 2022; 22278153.
[http://dx.doi.org/10.1101/2022.07.28.22278153]
[43]
Çelebi G, Pişkin N, Çelik Bekleviç A, et al. Specific risk factors for SARS-CoV-2 transmission among health care workers in a university hospital. Am J Infect Control 2020; 48(10): 1225-30.
[http://dx.doi.org/10.1016/j.ajic.2020.07.039] [PMID: 32771498]
[44]
Phan LT, Maita D, Mortiz DC, et al. Personal protective equipment doffing practices of healthcare workers. J Occup Environ Hyg 2019; 16(8): 575-81.
[http://dx.doi.org/10.1080/15459624.2019.1628350] [PMID: 31291152]
[45]
Verbeek JH, Rajamaki B, Ijaz S, et al. Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staff. Cochrane Database Syst Rev 2020; 4(4): CD011621.
[http://dx.doi.org/10.1002/14651858.CD011621] [PMID: 32293717]
[46]
Wee LE, Sim XYJ, Conceicao EP, et al. Containment of COVID-19 cases among healthcare workers: The role of surveillance, early detection, and outbreak management. Infect Control Hosp Epidemiol 2020; 41(7): 765-71.
[http://dx.doi.org/10.1017/ice.2020.219] [PMID: 32391746]
[47]
SeyedAlinaghi S, Karimi A, Pashaei Z, et al. Post-exposure prophylaxis for COVID-19: A systematic review. Infect Disord Drug Targets 2023. Epub ahead of print
[http://dx.doi.org/10.2174/1871526523666230413082721] [PMID: 37069717]
[48]
Mehraeen E, Najafi Z, Hayati B, et al. Current treatments and therapeutic options for COVID-19 patients: A systematic review. Infect Disord Drug Targets 2022; 22(1): e260721194968.
[http://dx.doi.org/10.2174/1871526521666210726150435] [PMID: 34313204]
[49]
Dehghani S. SeyedAlinaghi S, Karimi A, et al. Evaluating the effects of air disinfectants in decontamination of COVID-19 aerosols. Health Sci Rep 2023; 6(1): e1042.
[http://dx.doi.org/10.1002/hsr2.1042] [PMID: 36644313] [PMCID: PMC9831143]
[50]
Mehraeen E, Paranjkhoo P. SeyedAlinaghi S, Hackett D. Social avoidance and emotional deprivation of healthcare providers during the COVID-19 pandemic. Infect Disord Drug Targets 2023. Epub ahead of print.
[http://dx.doi.org/10.2174/1871526523666230516155643] [PMID: 37194230]
[51]
SeyedAlinaghi S, Afsahi AM, MohsseniPour M, et al. Late complications of COVID-19; a systematic review of current evidence. Arch Acad Emerg Med 2021; 9(1): e14.
[http://dx.doi.org/10.22037/aaem.v9i1.1058] [PMID: 33681819]
[52]
SeyedAlinaghi S, Abbasian L, Solduzian M, et al. Predictors of the prolonged recovery period in COVID-19 patients: a cross-sectional study. Eur J Med Res 2021; 26(1): 41.
[http://dx.doi.org/10.1186/s40001-021-00513-x] [PMID: 33957992]
[53]
Dadras O, Afsahi AM, Pashaei Z, et al. The relationship between COVID-19 viral load and disease severity: A systematic review. Immun Inflamm Dis 2022; 10(3): e580.
[http://dx.doi.org/10.1002/iid3.580] [PMID: 34904379]
[54]
Mohammad H, Elham M, Mehraeen E, et al. Identifying data elements and key features of a mobile-based self-care application for patients with COVID-19 in Iran. Health Informatics J 2021; 27(4): 14604582211065703.
[http://dx.doi.org/10.1177/14604582211065703] [PMID: 34936526]

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