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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Synthesis of 5-Substituted-1,3,4-Oxadiazole-2(3H)-Thiones Under Microwave Irradiation

Author(s): Wolfgang Voelter, Awais Anwar, Muhammad Ali, Shahnaz Perveen, Mubeen Rani, Sohail A. Shahzad and Khalid M. Khan

Volume 3, Issue 4, 2006

Page: [286 - 288] Pages: 3

DOI: 10.2174/157017806776114522

Price: $65

Abstract

A variety of 5-substituted-1,3,4-oxadiazole-2(3H)-thiones were prepared using microwave irradiation as energy source under solvent-free conditions. Reaction times were reduced from 5-14 h to 3-7 min affording high yields from corresponding acyl and aroyl hydrazides.

Keywords: microwave-assisted synthesis, 4-oxadiazolethiones, 5-substituted-1,3


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