Abstract
CD4C/HIVNef Tg mice express HIV-1 Nef in relevant target cells through the regulatory sequences of the human CD4 gene. These mice develop a severe disease showing many characteristics of human AIDS. A summary of the results obtained with these Tg mice is presented.
Keywords: HIV-1, Nef, mouse model, AIDS, SIV, HIVAN, CD4C/HIVNef, Transgene, Tg DC, AIDS-LIKE DISEASE
Current HIV Research
Title: The CD4C/HIVNef Transgenic Model of AIDS
Volume: 9 Issue: 7
Author(s): Paul Jolicoeur
Affiliation:
Keywords: HIV-1, Nef, mouse model, AIDS, SIV, HIVAN, CD4C/HIVNef, Transgene, Tg DC, AIDS-LIKE DISEASE
Abstract: CD4C/HIVNef Tg mice express HIV-1 Nef in relevant target cells through the regulatory sequences of the human CD4 gene. These mice develop a severe disease showing many characteristics of human AIDS. A summary of the results obtained with these Tg mice is presented.
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Cite this article as:
Jolicoeur Paul, The CD4C/HIVNef Transgenic Model of AIDS, Current HIV Research 2011; 9 (7) . https://dx.doi.org/10.2174/157016211798842062
DOI https://dx.doi.org/10.2174/157016211798842062 |
Print ISSN 1570-162X |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4251 |
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