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Current Vascular Pharmacology

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ISSN (Print): 1570-1611
ISSN (Online): 1875-6212

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Review Article

Rationale for the Concept of Impending Hypertension-Mediated Organ Damage

Author(s): Goran Koracevic, Milovan Stojanovic*, Dragan Lovic, Radmila Velickovic Radovanovic and Maja Koracevic

Volume 20, Issue 2, 2022

Published on: 16 February, 2022

Page: [127 - 133] Pages: 7

DOI: 10.2174/1570161120666220124105846

Price: $65

Abstract

Background: The number of patients with hypertension urgencies (HTN-Us) and emergencies (HTN-Es) in the emergency department is relatively constant despite improved detection, awareness and control of arterial hypertension.

Objective: This study analyses the precision of the often-used definition of HTN-E, particularly the phrase ‘with the evidence of impending or progressive hypertension-mediated organ damage (HMOD)’. We then provide a rationale for the concept of impending HMOD.

Methods: The databases PubMed, Science Direct, Springer, Oxford Press, Wiley, SAGE and Google Scholar were searched and the relevant definition has been analyzed.

Results: The definition of HTN-E is suboptimal and requires a consensus on whether to include the phrase ‘impending hypertensive HMOD’ in the definition.

Conclusion: A consensus on the principles of treating the ‘impending hypertensive HMOD’ does not exist, making its use inconsistent in emergency departments worldwide. In this paper, we present a rationale for the concept of ‘impending HMOD’.

Keywords: Hypertensive emergencies, hypertensive urgencies, impending hypertension-mediated organ damage, impending target organ damage, cholesterol, patients.

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Graphical Abstract

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