Abstract
A large amount of pesticides are being used now-a-days in crop protection which has resulted in buildup of such harmful compounds in the environment, proving a menace to humans, animal life as well as to soil microbes. Residues of these pesticides have been reported in soil, water and foods. Carbendazim and sulfosulfuron are among the most widely used pesticides for treating fungal diseases and unwanted herbs in crops respectively. Carbendazim is a benzimidazole fungicide which can harm liver as well as the endocrine system and is suspected to have mutagenic and tumorigenic effects. On similar lines sulfosulfuron, a sulfonylurea herbicide may result in the development of resistant herbs displaying its carry-over effects to the next crop cultivated. These pesticides possess large half-lives and thus remain persistent in the environment which may lead to harmful consequences in the near future. Besides chemical and photo-catalytic degradation of pesticides, microbial degradation has now been evolved as a much effective and safer way to eradicate these harmful compounds from the environment. However a limited literature is available on the microbial degradation of such compounds. The present review emphasizes mainly upon the chemical properties of Carbendazim and Sulfosulfuron, detection of their residues, harmful effects and insights into their degradation studies. Further, the use of efficient microbes for remediation of pesticides from the environment has been discussed.
Keywords: Carbendazim, degradation, microbial community, pesticides, residues, sulfosulfuron.
Current Medicinal Chemistry
Title:Biodegradation Aspects of Carbendazim and Sulfosulfuron: Trends, Scope and Relevance
Volume: 22 Issue: 9
Author(s): R. Arya, R. Sharma, M. Malhotra, V. Kumar and A.K. Sharma
Affiliation:
Keywords: Carbendazim, degradation, microbial community, pesticides, residues, sulfosulfuron.
Abstract: A large amount of pesticides are being used now-a-days in crop protection which has resulted in buildup of such harmful compounds in the environment, proving a menace to humans, animal life as well as to soil microbes. Residues of these pesticides have been reported in soil, water and foods. Carbendazim and sulfosulfuron are among the most widely used pesticides for treating fungal diseases and unwanted herbs in crops respectively. Carbendazim is a benzimidazole fungicide which can harm liver as well as the endocrine system and is suspected to have mutagenic and tumorigenic effects. On similar lines sulfosulfuron, a sulfonylurea herbicide may result in the development of resistant herbs displaying its carry-over effects to the next crop cultivated. These pesticides possess large half-lives and thus remain persistent in the environment which may lead to harmful consequences in the near future. Besides chemical and photo-catalytic degradation of pesticides, microbial degradation has now been evolved as a much effective and safer way to eradicate these harmful compounds from the environment. However a limited literature is available on the microbial degradation of such compounds. The present review emphasizes mainly upon the chemical properties of Carbendazim and Sulfosulfuron, detection of their residues, harmful effects and insights into their degradation studies. Further, the use of efficient microbes for remediation of pesticides from the environment has been discussed.
Export Options
About this article
Cite this article as:
Arya R., Sharma R., Malhotra M., Kumar V. and Sharma A.K., Biodegradation Aspects of Carbendazim and Sulfosulfuron: Trends, Scope and Relevance, Current Medicinal Chemistry 2015; 22 (9) . https://dx.doi.org/10.2174/0929867322666141212123449
DOI https://dx.doi.org/10.2174/0929867322666141212123449 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
Call for Papers in Thematic Issues
Advances in Medicinal Chemistry: From Cancer to Chronic Diseases.
The broad spectrum of the issue will provide a comprehensive overview of emerging trends, novel therapeutic interventions, and translational insights that impact modern medicine. The primary focus will be diseases of global concern, including cancer, chronic pain, metabolic disorders, and autoimmune conditions, providing a broad overview of the advancements in ...read more
Approaches to the treatment of chronic inflammation
Chronic inflammation is a hallmark of numerous diseases, significantly impacting global health. Although chronic inflammation is a hot topic, not much has been written about approaches to its treatment. This thematic issue aims to showcase the latest advancements in chronic inflammation treatment and foster discussion on future directions in this ...read more
Cellular and Molecular Mechanisms of Non-Infectious Inflammatory Diseases: Focus on Clinical Implications
The Special Issue covers the results of the studies on cellular and molecular mechanisms of non-infectious inflammatory diseases, in particular, autoimmune rheumatic diseases, atherosclerotic cardiovascular disease and other age-related disorders such as type II diabetes, cancer, neurodegenerative disorders, etc. Review and research articles as well as methodology papers that summarize ...read more
Chalcogen-modified nucleic acid analogues
Chalcogen-modified nucleosides, nucleotides and oligonucleotides have been of great interest to scientific research for many years. The replacement of oxygen in the nucleobase, sugar or phosphate backbone by chalcogen atoms (sulfur, selenium, tellurium) gives these biomolecules unique properties resulting from their altered physical and chemical properties. The continuing interest in ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Novel Series of Coumarinyl Substituted-thiazolidin-2,4-dione Analogs as Anticancer Agents: Design, Synthesis, Spectral Studies and Cytotoxicity Evaluation
Anti-Cancer Agents in Medicinal Chemistry Hepatic Stellate Cell: A Potential Target for Hepatocellular Carcinoma
Current Molecular Pharmacology Mathematical Nanotoxicoproteomics: Quantitative Characterization of Effects of Multi-walled Carbon Nanotubes (MWCNT) and TiO2 Nanobelts (TiO2-NB) on Protein Expression Patterns in Human Intestinal Cells
Current Computer-Aided Drug Design Mechanism of Action of Flavonoids in Prevention of Inflammation- Associated Skin Cancer
Current Medicinal Chemistry Anti-Inflammatory Drugs and Prediction of New Structures by Comparative Analysis
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Proteomics as a Tool in the Pharmaceutical Drug Design Process
Current Pharmaceutical Design Novel Somatic Mutations of the CDH1 Gene Associated with Gastric Cancer: Prediction of Pathogenicity Using Comprehensive In silico Methods
Current Pharmacogenomics and Personalized Medicine Characterization of Pharmaceutical IgG and Biosimilars Using Miniaturized Platforms and LC-MS/MS
Current Pharmaceutical Biotechnology Recent Advances in Substrate Identification of Protein Kinases in Plants and Their Role in Stress Management
Current Genomics Synthesis and in vitro Anti-tumor Activity of Some New Sebacoyl Chloride Based Heterocycles
Current Organic Synthesis Machine Learning-Based Virtual Screening Strategy RevealsSome Natural Compounds as Potential PAK4 Inhibitors in Triple Negative Breast Cancer
Current Proteomics Killer Beacons for Combined Cancer Imaging and Therapy
Current Medicinal Chemistry Occupational Risk Assessment of Engineered Nanomaterials: Limits, Challenges and Opportunities
Current Nanoscience Ketamine for Chronic Pain and Treatment Resistant Depression: A Mechanistic Hypothesis
Current Drug Therapy The Isoprostanes - Unique Products of Arachidonate Peroxidation: Their Role as Mediators of Oxidant Stress
Current Pharmaceutical Design Unexpected High Levels of Vorinostat when Combined with Vinorelbine in Patients with Advanced Cancer
Current Clinical Pharmacology An Overview of 7α- and 7β-Hydroxysteroid Dehydrogenases: Structure, Specificity and Practical Application
Protein & Peptide Letters Chemical Proteomics to Identify Molecular Targets of Small Compounds
Current Molecular Medicine Structure Activity Relationship of Arylidene Pyrrolo and Pyrido [2,1-b] Quinazolones as Cytotoxic Agents: Synthesis, SAR Studies, Biological Evaluation and Docking Studies
Medicinal Chemistry Anti-inflammatory, Antioxidant, Lung and Liver Protective Activity of <i>Galaxaura oblongata</i> as Antagonistic Efficacy against LPS using Hematological Parameters and Immunohistochemistry as Biomarkers
Cardiovascular & Hematological Agents in Medicinal Chemistry