Abstract
Water has proved to be an excellent reaction medium for the definition of highly chemically-efficient and environmentallyfriendly synthetic processes. In several cases, by exploiting the unique properties of water it has been possible to realize more selective and efficient processes than those performed in organic media, including the ring-opening of epoxides by nucleophiles. In this review article the role of water in influencing the stereoselectivity of epoxide ring-opening reactions will be presented, including the most recent examples of enzyme-catalyzed processes.
Keywords: Epoxide, water, stereoselective transformations, catalysis, synthetic processes, organic, ring-opening reactions, nucleophiles, species, acids
Current Organic Synthesis
Title: Stereoselective Ring-Opening Reactions of Epoxides in Water
Volume: 8 Issue: 3
Author(s): S. Bonollo, D. Lanari, A. Marrocchi and L. Vaccaro
Affiliation:
Keywords: Epoxide, water, stereoselective transformations, catalysis, synthetic processes, organic, ring-opening reactions, nucleophiles, species, acids
Abstract: Water has proved to be an excellent reaction medium for the definition of highly chemically-efficient and environmentallyfriendly synthetic processes. In several cases, by exploiting the unique properties of water it has been possible to realize more selective and efficient processes than those performed in organic media, including the ring-opening of epoxides by nucleophiles. In this review article the role of water in influencing the stereoselectivity of epoxide ring-opening reactions will be presented, including the most recent examples of enzyme-catalyzed processes.
Export Options
About this article
Cite this article as:
Bonollo S., Lanari D., Marrocchi A. and Vaccaro L., Stereoselective Ring-Opening Reactions of Epoxides in Water, Current Organic Synthesis 2011; 8 (3) . https://dx.doi.org/10.2174/157017911795529191
DOI https://dx.doi.org/10.2174/157017911795529191 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
Call for Papers in Thematic Issues
Design and Synthesis of Green Pesticides
The development of green new pesticides is currently one of the hotspots in the field of pesticide research, aiming to develop efficient, environmentally friendly, and safe pesticide products to meet the needs of modern agricultural production. Green new pesticides prioritize environmental friendliness and ecological safety. Therefore, during the research and ...read more
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
Organic Radical Chemistry
Organic radical chemistry has a history of more than 110 years. In the past decade, we have witnessed new directions for organic radical chemistry. It has now become an exciting area of research in organic chemistry, and new discoveries can be seen every day in various aspects of radical chemistry ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers