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Current HIV Research

Editor-in-Chief

ISSN (Print): 1570-162X
ISSN (Online): 1873-4251

HIV-1 CRF_BC Recombinants Infection in China: Molecular Epidemic and Characterizations

Author(s): Yabo Ouyang, Yiming Shao and Liying Ma

Volume 10, Issue 2, 2012

Page: [151 - 161] Pages: 11

DOI: 10.2174/157016212799937236

Price: $65

Abstract

CRF_BC recombinant strains were first identified in China and are one of the most prevalent and characteristically unique HIV-1 subtypes across China. Here we aim to review the published data about HIV-1 CRF_BC recombinant strains epidemic in China and to characterize the genetics, biology and drug resistance of this virus. This study may help to better understand the current situation of HIV-1 CRF_BC prevalence and facilitate the development of vaccines and more efficient anti-HIV-1 regimens in China.

Keywords: AIDS, HIV-1, CRF_BC, epidemic, genetic, biologic and drug resistant


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