Abstract
Tumor-targeted chemo- or gene-therapies is a new form of treatment which provides the benefits ofreducing systemic toxicity, increasing the tolerance, and enhancing therapeutic efficacy. This review willdiscuss the discovery, function, application, and mechanism by which the short peptides (5-9) work for tumor-targeted gene or drug delivery.
Keywords: Peptide, tumor-targeting, tumor vessel, gene therapy, gene delivery, drug delivery, adhesion molecule, phage display
Mini-Reviews in Medicinal Chemistry
Title: Function and Molecular Mechanism of Tumor-Targeted Peptides for Delivering Therapeutic Genes and Chemical Drugs
Volume: 6 Issue: 7
Author(s): Ryan Craig and Shulin Li
Affiliation:
Keywords: Peptide, tumor-targeting, tumor vessel, gene therapy, gene delivery, drug delivery, adhesion molecule, phage display
Abstract: Tumor-targeted chemo- or gene-therapies is a new form of treatment which provides the benefits ofreducing systemic toxicity, increasing the tolerance, and enhancing therapeutic efficacy. This review willdiscuss the discovery, function, application, and mechanism by which the short peptides (5-9) work for tumor-targeted gene or drug delivery.
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Cite this article as:
Craig Ryan and Li Shulin, Function and Molecular Mechanism of Tumor-Targeted Peptides for Delivering Therapeutic Genes and Chemical Drugs, Mini-Reviews in Medicinal Chemistry 2006; 6 (7) . https://dx.doi.org/10.2174/138955706777698615
DOI https://dx.doi.org/10.2174/138955706777698615 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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