Abstract
Over the second half of 20th century much research on lipogenesis has been conducted, especially focused on increasing the production efficiency and improving the quality of animal derived products. However, many diferences are observed in the physiology of lipogenesis between species. Recently, many studies have also elucidated the involvement of numerous genes in this procedure, highlighting diferences not only at physiology but also at the molecular level. The main scope of this review is to point out the major differences between ruminant and non ruminant species, that are observed in key regulatory genes involved in lipogenesis. Human is used as a central reference and according to the findinggs, main differences are analysed. These findings could serve not only as basis for understanding the main physiology of lipogenesis and further basic research, but also as a basis for any animal scientist to develop new concepts and methods for use in improving animal production and modern genetic improvement.
Keywords: Fatty acids, genes, lipogenesis, ruminants, sheep
Current Genomics
Title: Comparative Approach of the de novo Fatty Acid Synthesis (Lipogenesis) between Ruminant and Non Ruminant Mammalian Species: From Biochemical Level to the Main Regulatory Lipogenic Genes
Volume: 11 Issue: 3
Author(s): G.P. Laliotis, I. Bizelis and E. Rogdakis
Affiliation:
Keywords: Fatty acids, genes, lipogenesis, ruminants, sheep
Abstract: Over the second half of 20th century much research on lipogenesis has been conducted, especially focused on increasing the production efficiency and improving the quality of animal derived products. However, many diferences are observed in the physiology of lipogenesis between species. Recently, many studies have also elucidated the involvement of numerous genes in this procedure, highlighting diferences not only at physiology but also at the molecular level. The main scope of this review is to point out the major differences between ruminant and non ruminant species, that are observed in key regulatory genes involved in lipogenesis. Human is used as a central reference and according to the findinggs, main differences are analysed. These findings could serve not only as basis for understanding the main physiology of lipogenesis and further basic research, but also as a basis for any animal scientist to develop new concepts and methods for use in improving animal production and modern genetic improvement.
Export Options
About this article
Cite this article as:
Laliotis G.P., Bizelis I. and Rogdakis E., Comparative Approach of the de novo Fatty Acid Synthesis (Lipogenesis) between Ruminant and Non Ruminant Mammalian Species: From Biochemical Level to the Main Regulatory Lipogenic Genes, Current Genomics 2010; 11 (3) . https://dx.doi.org/10.2174/138920210791110960
DOI https://dx.doi.org/10.2174/138920210791110960 |
Print ISSN 1389-2029 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5488 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Yeast Genomics and Drug Target Identification
Combinatorial Chemistry & High Throughput Screening Recent Patents on Antibacterial, Antifungal and Antiviral Properties of Tea
Recent Patents on Anti-Infective Drug Discovery New Quinolinyl–1,3,4–Oxadiazoles: Synthesis, In Vitro Antibacterial, Antifungal and Antituberculosis Studies
Medicinal Chemistry Molecularly Imprinted Polymer of Colocynthin, An Effective Tool for Quality Control of <i>Citrullus colocynthis</i> Extracts
Current Drug Discovery Technologies Recent Innovations in Antibody-Mediated, Targeted Particulate Nanotechnology and Implications for Advanced Visualisation and Drug Delivery
Current Nanoscience One-Pot Three-Component Synthesis and Molecular Docking of Some Novel 2-Thiazolyl Pyridines as Potent Antimicrobial Agents
Mini-Reviews in Medicinal Chemistry Revealing the Promoting Effect of Betaine on Vitamin B<sub>12</sub> Biosynthetic Pathway of <i>Pseudomonas denitrificans</i> by Using a Proteomics Analysis
Current Pharmaceutical Biotechnology Next Generation Sequencing in Non-Small Cell Lung Cancer: New Avenues Toward the Personalized Medicine
Current Drug Targets Analgesic and Antineuropathic Drugs Acting Through Central Cholinergic Mechanisms
Recent Patents on CNS Drug Discovery (Discontinued) Genetic and Modifying Factors that Determine the Risk of Brain Tumors
Central Nervous System Agents in Medicinal Chemistry Protein/Polyphenol Interactions: Past and Present Contributions. Mechanisms of Astringency Perception
Current Organic Chemistry Glyco-Engineering of Human IgG-Fc to Modulate Biologic Activities
Current Pharmaceutical Biotechnology Applications of HPLC-MALDI-TOF MS/MS Phosphoproteomic Analysis in Oncological Clinical Diagnostics
Current Proteomics Carbon Nanotube Based DNA Biosensor for Rapid Detection of Anti-Cancer Drug of Cyclophosphamide
Current Nanoscience Electrochemical Metal Sensors with DNA Receptor Layers
Current Analytical Chemistry Natural Compounds Used as Therapies Targeting to Amyotrophic Lateral Sclerosis
Current Pharmaceutical Biotechnology Non-allowed Pharmacologically Active Substances in Physical and Sexual Performance Enhancing Products
Current Neuropharmacology Liposomes Prepared in Absence of Organic Solvents: Sonication Versus Lipid Film Hydration Method
Current Pharmaceutical Analysis Zinc Homeostasis-regulating Proteins: New Drug Targets for Triggering Cell Fate
Current Drug Targets Application of Metabolomics in Drug Discovery, Development and Theranostics
Current Metabolomics