Cerebral Infarction and Myalgia in a 75-year-old Man with Eosinophilic Granulomatosis with Polyangiitis

Yuki Ueta; Yuki Akiba; Jun Yamazaki; Yoshihiko Okubo; Takeshi Taguchi; Hiroo Terashi; Yukiko K. Hayashi; Hitoshi Aizawa

doi:10.2169/internalmedicine.5099-20

CASE REPORTS

Cerebral Infarction and Myalgia in a 75-year-old Man with Eosinophilic Granulomatosis with Polyangiitis

Yuki Ueta, Yuki Akiba, Jun Yamazaki, Yoshihiko Okubo, Takeshi Taguchi, Hiroo Terashi, Yukiko K. Hayashi, Hitoshi Aizawa

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Keywords: eosinophilic granulomatosis with polyangiitis (EGPA), Churg-Strauss syndrome, cerebral infarction, myalgia, muscle biopsy, corticosteroid therapy

JOURNAL OPEN ACCESS

2020 Volume 59 Issue 23 Pages 3089-3092

DOI https://doi.org/10.2169/internalmedicine.5099-20

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Abstract

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare condition of systemic vasculitis of small to medium-sized blood vessels. We herein report the case of a 75-year-old man who presented with hemiplegia on his right side due to cerebral infarction following myalgia and a high fever. He had no history of asthma or allergic rhinitis. He was diagnosed with EGPA based on the presence of eosinophilia, sinusitis suggested by magnetic resonance imaging, and muscle pathology. His hemiplegia improved rapidly after corticosteroid therapy. This case suggests that EGPA should be a differential diagnosis of cerebral infarction with myalgia and eosinophilia.

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