Pulmonary Hyalinizing Granuloma with Laryngeal and Subcutaneous Involvement: Report of a Case Successfully Treated with Glucocorticoids

Takeshi SHINOHARA; Takeshi KANEKO; Naoki MIYAZAWA; Yukio NAKATANI; Harumi NISHIYAMA; Akira SHOJI; Yoshiaki ISHIGATSUBO

doi:10.2169/internalmedicine.43.69

Respiratory Diseases

Pulmonary Hyalinizing Granuloma with Laryngeal and Subcutaneous Involvement: Report of a Case Successfully Treated with Glucocorticoids

Takeshi SHINOHARA, Takeshi KANEKO, Naoki MIYAZAWA, Yukio NAKATANI, Harumi NISHIYAMA, Akira SHOJI, Yoshiaki ISHIGATSUBO

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Keywords: pulmonary hyalinizing granuloma, inflammatory pseudotumor, human herpesvirus-8, systemic idiopathic fibrosis, mediastinal fibrosis

JOURNAL OPEN ACCESS

2004 Volume 43 Issue 1 Pages 69-73

DOI https://doi.org/10.2169/internalmedicine.43.69

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Abstract

We report a case of pulmonary hyalinizing granuloma (PHG) with laryngeal and subcutaneous involvement. A 43-year-old man was admitted to our hospital for assessment of hoarseness. Cervical and chest computed tomography, respectively, revealed a laryngeal tumor and two pulmonary masses. Specimens obtained from the pulmonary masses were compatible with PHG. The histopathology of biopsy specimens from both the laryngeal tumor and a subcutaneous tumor resembled that of the resected lung masses. Although there is no established treatment for PHG, the laryngeal tumor was diminished and all other lesions disappeared with glucocorticoid treatment.

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