Multiple-line Chemotherapy for a Patient with Unresectable Mucinous Cystic Neoplasm of the Pancreas

Haruo Miwa; Kazuya Sugimori; Tomohiro Ishii; Akihiro Funaoka; Hiromi Tsuchiya; Yoshimasa Suzuki; Makoto Sugimori; Masaki Nishimura; Yuichiro Tozuka; Satoshi Komiyama; Takeshi Sato; Takashi Kaneko; Kazushi Numata; Shin Maeda

doi:10.2169/internalmedicine.6755-20

CASE REPORTS

Multiple-line Chemotherapy for a Patient with Unresectable Mucinous Cystic Neoplasm of the Pancreas

Haruo Miwa, Kazuya Sugimori, Tomohiro Ishii, Akihiro Funaoka, Hiromi Tsuchiya, Yoshimasa Suzuki, Makoto Sugimori, Masaki Nishimura, Yuichiro Tozuka, Satoshi Komiyama, Takeshi Sato, Takashi Kaneko, Kazushi Numata, Shin Maeda

Author information

Haruo Miwa
Gastroenterological Center, Yokohama City University Medical Center, Japan
Kazuya Sugimori
Gastroenterological Center, Yokohama City University Medical Center, Japan
Tomohiro Ishii
Gastroenterological Center, Yokohama City University Medical Center, Japan
Akihiro Funaoka
Gastroenterological Center, Yokohama City University Medical Center, Japan
Hiromi Tsuchiya
Gastroenterological Center, Yokohama City University Medical Center, Japan
Yoshimasa Suzuki
Gastroenterological Center, Yokohama City University Medical Center, Japan
Makoto Sugimori
Gastroenterological Center, Yokohama City University Medical Center, Japan
Masaki Nishimura
Gastroenterological Center, Yokohama City University Medical Center, Japan
Yuichiro Tozuka
Gastroenterological Center, Yokohama City University Medical Center, Japan
Satoshi Komiyama
Gastroenterological Center, Yokohama City University Medical Center, Japan
Takeshi Sato
Gastroenterological Center, Yokohama City University Medical Center, Japan
Takashi Kaneko
Gastroenterological Center, Yokohama City University Medical Center, Japan
Kazushi Numata
Gastroenterological Center, Yokohama City University Medical Center, Japan
Shin Maeda
Division of Gastroenterology, Yokohama City University Graduate School of Medicine, Japan

Keywords: antineoplastic combined chemotherapy protocols, palliative therapy, pancreatic cancer, pancreatic cyst

JOURNAL OPEN ACCESS

2021 Volume 60 Issue 16 Pages 2607-2612

DOI https://doi.org/10.2169/internalmedicine.6755-20

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Details

Abstract

A 74-year-old woman with a cyst in her pancreatic tail was referred to our hospital. Computed tomography confirmed a large cystic lesion with irregular wall thickening, abdominal lymph node swelling, and ascites. We diagnosed her with an unresectable mucinous cystic neoplasm, since ascites cytology revealed adenocarcinoma. The patient received chemotherapy up to the fifth line for 55.2 months. Gemcitabine plus nab-paclitaxel and modified FOLFIRINOX achieved a partial response with a progression-free survival time of 12.1 and 20.4 months, respectively. The overall survival time from the beginning of first-line chemotherapy was 69.4 months.

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