Abstract
Maffucci syndrome is a rare, sporadic disease characterized by the development of multiple enchondromas and subcutaneous hemangiomas. Patients with Maffucci syndrome have a 23–37% risk of malignancy, with chondrosarcomas being the most common. Although the development of a chondrosarcoma in a patient with Maffucci syndrome may be expected, intracranial chondrosarcomas are rare. We present a patient with Maffucci syndrome who was diagnosed with an intracranial chondrosarcoma after presenting with hearing loss and vomiting. After three craniotomies and two recurrences of chondrosarcoma of the right skull base, the patient demonstrated a positive outcome to treatment with external radiation therapy.
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No sources of funding were used to assist in the preparation of this case report. The authors have no conflicts of interest that are directly relevant to the content of this case report.
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Abdelmalek, M., Stanko, C. Recurrent Chondrosarcoma of the Right Skull Base in a Patient with Maffucci Syndrome. Am J Clin Dermatol 9, 61–65 (2008). https://doi.org/10.2165/00128071-200809010-00008
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DOI: https://doi.org/10.2165/00128071-200809010-00008