CUSHINGS SYNDROME WITH BILATERAL ADRENAL MASSES: WHAT MANAGEMENT?
- Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital, Fez.
- Laboratory of Epidemiology and Research in Health Sciences, Faculty of Medicine and Pharmacy, Fez, Morocco.
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ACTH independent Cushings syndrome (CS) with bilateral adrenal masses is an extremely rare entity. Its management constitutes a challenge to clinicians due to difficulty of exact location of the functional lesions. We herein report a case of a 42-year-old patient with a heavy smoking history who presented a CS for 2 years. Serial examinations revealed ACTH independent CS and bilateral adrenal masses on adrenal computed tomography the largest was on the left measuring 30 x 27 mm. Then the patient underwent a laparoscopic adrenalectomy for left adrenal tumor which diagnosed as an adrenal cortical adenoma with a Weiss Score <2 by the pathological reports. The immediate post-operative course was marked by a corticotroph deficiency that was substituted. The removal of the largest adrenal lesion could represent a therapeutic alternative in the management of bilateral adrenal masses when functional and / or invasive exploration isnt available.
[Fatimazahrae Melki, Loubna Saadaoui, Houda Salhi and Hanan El Ouahabi (2022); CUSHINGS SYNDROME WITH BILATERAL ADRENAL MASSES: WHAT MANAGEMENT? Int. J. of Adv. Res. 10 (Apr). 311-314] (ISSN 2320-5407). www.journalijar.com
Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital, Fez
Morocco