Abstract
A molecularly imprinted polymer-modified potentiometric histamine (HIS) sensor was prepared and used for quantitative determination of HIS in bovine serum. The calibration curve using the potential responses measured in 1 × 10–3 mol L–1phosphate buffer (pH 7.4) showed good linearity in the HIS concentration range of 3 × 10–4 to 1 × 10–2 mol L–1 (r = 0.92), with a detection limit of 1.6 × 10–4 mol L–1. In bovine serum samples, the HIS sensor showed good recovery values of 91–104%. Therefore, this HIS sensor successfully determined the HIS concentration in bovine serum samples.
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Acknowledgments
This work was partly supported by grants from Leave a Nest Co., Ltd. with USHIO Inc. We thank Simon Partridge, PhD, from Edanz Group (www.edanzediting.com/ac) for editing a draft of this manuscript.
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Konishi, A., Takegami, S., Idosaki, Y. et al. Application of Molecularly Imprinted Polymer-modified Potentiometric Sensor for Quantitative Determination of Histamine in Serum. ANAL. SCI. 36, 1561–1563 (2020). https://doi.org/10.2116/analsci.20N018
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DOI: https://doi.org/10.2116/analsci.20N018