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Microfluidic Analysis with Front-Face Fluorometric Detection for the Determination of Total Inorganic Iodine in Drinking Water

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Abstract

A microfluidic method with front-face fluorometric detection was developed for the determination of total inorganic iodine in drinking water. A polydimethylsiloxane (PDMS) microfluidic device was employed in conjunction with the Sandell–Kolthoff reaction, in which iodide catalyzed the redox reaction between Ce(IV) and As(III). Direct alignment of an optical fiber attached to a spectrofluorometer was used as a convenient detector for remote front-face fluorometric detection. Trace inorganic iodine (IO3–and I–) present naturally in drinking water was measured by on-line conversion of iodate to iodide for determination of total inorganic iodine. On-line conversion efficiency of iodate to iodide using the microfluidic device was investigated. Excellent conversion efficiency of 93–103% (%RSD = 1.6–11%) was obtained. Inorganic iodine concentrations in drinking water samples were measured, and the results obtained were in good agreement with those obtained by an ICP-MS method. Spiked sample recoveries were in the range of 86%(±5)–128%(±8) (n = 12). Interference of various anions and cations were investigated with tolerance limit concentrations ranging from 10−6 to 2.5 M depending on the type of ions. The developed method is simple and convenient, and it is a green method for iodine analysis, as it greatly reduces the amount of toxic reagent consumed with reagent volumes in the microfluidic scale.

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Acknowledgments

This work was supported by the Thailand Research Fund (A5580021 to DN and RGJ-Ph.D. Scholarship to P. Inpota), Faculty of Science, Mahidol Univestity, Center of Excellence for Innovation in Chemistry (PERCH-CIC), Commission on Higher Education, Ministry of Education, and Office of Higher Education Commission and Mahidol University under the National Research Universities Initiative. Financial support from the EU through the European Social Fund, contract number UDA-POKL.04.01.01-00-072/09-00 given to K. S. is gratefully thanked.

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Authors and Affiliations

  1. Center of Excellence for Innovation in Chemistry and Department of Chemistry, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok, 10400, Thailand

    Prawpan Inpota, Rattikan Chantiwas & Duangjai Nacapricha

  2. Flow Innovation Research for Science and Technology Laboratories (FIRST Labs.), Thailand

    Prawpan Inpota, Nuanlaor Ratanawimarnwong, Prapin Wilairat, Nathawut Choengchan, Rattikan Chantiwas & Duangjai Nacapricha

  3. Department of Chemistry, Pasteura I, University of Warsaw, 02-093, Warsaw, Poland

    Kamil Strzelak & Robert Koncki

  4. Thai Microelectronics Center (TMEC), Chachoengsao, 24000, Thailand

    Wisaroot Sripumkhai & Wutthinan Jeamsaksiri

  5. Department of Chemistry, Faculty of Science, Srinakharinwirot University, Sukhumwit 23, Bangkok, 10110, Thailand

    Nuanlaor Ratanawimarnwong

  6. National Doping Control Centre, Mahidol University, Rama 6 Road, Bangkok, 10400, Thailand

    Prapin Wilairat

  7. Department of Chemistry and the Applied Analytical Chemistry! Research Unit, Faculty of Science, King Mongkut’s Institute of Technology Ladkrabang, Chalongkrung Road, Bangkok, 10520, Thailand

    Nathawut Choengchan

Authors
  1. Prawpan Inpota
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  2. Kamil Strzelak
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  3. Robert Koncki
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  4. Wisaroot Sripumkhai
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  5. Wutthinan Jeamsaksiri
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  6. Nuanlaor Ratanawimarnwong
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  7. Prapin Wilairat
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  8. Nathawut Choengchan
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  9. Rattikan Chantiwas
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  10. Duangjai Nacapricha
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Corresponding authors

Correspondence to Nathawut Choengchan, Rattikan Chantiwas or Duangjai Nacapricha.

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Inpota, P., Strzelak, K., Koncki, R. et al. Microfluidic Analysis with Front-Face Fluorometric Detection for the Determination of Total Inorganic Iodine in Drinking Water. ANAL. SCI. 34, 161–167 (2018). https://doi.org/10.2116/analsci.34.161

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  • DOI: https://doi.org/10.2116/analsci.34.161

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