Abstract
A novel biochemical sensor was fabricated on a carbon fiber microelectrode, which consisted of an inner layer of electrodeposited gold nanoparticles, as a nano-array electrode, and an outer layer of electrodeposited calf thymus ds-DNA at +1. 5 V vs. SCE. This modified electrode was characterized by X-ray photoelectron spectroscopy, scanning electron microscope, atomic force microscopy, cyclic voltammetry and differential pulse voltammetry (DPV). It was found that this electrochemical sensor exhibits a strong catalytic activity toward the oxidation of dopamine (DA), serotonin (5-HT) and ascorbic acid (AA), as a result of resolving the anodic voltammetric peaks of DA, 5-HT and AA into three well-defined peaks. Simutaneous DPV determination of DA and 5-HT can be achieved in the presence of 2000-fold AA. The modified electrode shows good sensitivity, selectivity and stability.
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Lu, L., Wang, S. & Lin, X. Attachment of DNA to the Carbon Fiber Microelectrode via Gold Nanoparticles for Simultaneous Determination of Dopamine and Serotonin. ANAL. SCI. 20, 1131–1135 (2004). https://doi.org/10.2116/analsci.20.1131
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DOI: https://doi.org/10.2116/analsci.20.1131