This chapter examines challenges to the delivery of quality perinatal palliative care when that care is provided by more than one healthcare delivery system. It presents a quality improvement framework that can facilitate program development and improve access across delivery systems. The chapter also presents a case that demonstrates a variety of systems barriers that can occur in the delivery of perinatal palliative care and hospice. The case also highlights how maternal clinicians, inpatient pediatric clinicians, outpatient teams, and home health providers can collaborate to overcome such barriers. The chapter then describes the different healthcare delivery systems for perinatal and neonatal palliative care, including hospital, clinic, community, and home-based care. It discusses the challenges these different delivery systems pose to care delivery, and explains how to provide seamless care across the continuum of healthcare delivery systems for perinatal and neonatal care.