Title |
Methods for VHEE/FLASH Radiotherapy Studies and High Dose Rate Dosimetry at the CLEAR User Facility |
Authors |
- P. Korysko
Oxford University, Physics Department, Oxford, Oxon, United Kingdom
- J.J. Bateman, C.S. Robertson
JAI, Oxford, United Kingdom
- R. Corsinipresenter, L.A. Dyks, W. Farabolini, V. Rieker
CERN, Meyrin, Switzerland
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Abstract |
The interest for Very High Energy Electron (VHEE) radiotherapy (RT) for cancer treatment recently bloomed, given the present availability of high-gradient accelerator technology for compact, cost effective electron linacs in the 100-200 MeV energy range. Particularly promising is the so called FLASH high dose rate regime, in which cancer cells are damaged while healthy tissue is largely spared. VHEE beams are especially adapted for FLASH RT, given their penetration depth and the high beam current, needed to treat large deep seated tumors. In the CERN Linear Accelerator for Research (CLEAR) facility, a series of unique studies have been initiated on VHEE and FLASH RT issues, in collaboration with several multidisciplinary user groups. In this paper we briefly outline the activities and its main recent results, e.g. on localized dose deposition by beam focusing, and on chemical and biological test to clarify damage mechanisms. We then describe in details the dedicated systems and the techniques adopted - and in large part locally developed by the CLEAR team - in order to satisfy the user requirements, with particular attention to the crucial aspect of high dose rate dosimetry.
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Paper |
download THPOPA06.PDF [1.601 MB / 4 pages] |
Slides |
download THPOPA06_TALK.PDF [1.183 MB] |
Cite |
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Conference |
LINAC2022 |
Series |
International Linear Accelerator Conference (31st) |
Location |
Liverpool, UK |
Date |
28 August-02 September 2022 |
Publisher |
JACoW Publishing, Geneva, Switzerland |
Editorial Board |
Peter McIntosh (STFC DL, Daresbury, UK); Graeme Burt (Lancaster Univ., Lancaster, UK); Robert Apsimon (Lancaster Univ., Lancaster, UK); Volker R.W. Schaa (GSI, Darmstadt, Germany) |
Online ISBN |
978-3-95450-215-8 |
Online ISSN |
2226-0366 |
Received |
17 August 2022 |
Revised |
22 August 2022 |
Accepted |
31 August 2022 |
Issue Date |
16 October 2022 |
DOI |
doi:10.18429/JACoW-LINAC2022-THPOPA06 |
Pages |
758-761 |
Copyright |
Published by JACoW Publishing under the terms of the Creative Commons Attribution 4.0 International license. Any further distribution of this work must maintain attribution to the author(s), the published article's title, publisher, and DOI. |
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