| Title |
First Production of Astatine-211 at Crocker Nuclear Laboratory at UC Davis |
| Authors |
- E. Prebys, D.A. Cebra, R.B. Kibbee, L.M. Korkeila, K.S. Stewart
UCD, Davis, California, USA
- M.R. Backfish
UC Davis, Davis, USA
|
| Abstract |
There is a great deal of interest in the medical community in the use of the alpha-emitter At-211 as a therapeutic isotope. Among other things, its 7.2 hour half life is long enough to allow for recovery and labeling, but short enough to avoid long term activity in patients. Unfortunately, the only practical technique for its production is to bombard a Bi-209 target with a ~29 MeV alpha beam, so it is not accessible to commercial isotope production facilities, which all use fixed energy proton beams. The US Department of Energy is therefore supporting the development of a "University Isotope Network" (UIN) to satisfy this need. As part of this effort, we have developed an At-211 production facility using the variable-energy, multi-species cyclotron at Crocker Nuclear Lab the University of California, Davis. This effort relies on a beam probe which has been modified to serve as an internal Bi-209 target, to avoid problems with alpha particle extraction efficiency. This poster will data on the first production and recovery of At-211 using this system.
|
| Funding |
This work partially supported by the US DOE under contract DE-SC0020407 |
| Paper |
download THPOMS035.PDF [1.542 MB / 3 pages] |
| Cite |
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※ EndNote |
| Conference |
IPAC2022 |
| Series |
International Particle Accelerator Conference (13th) |
| Location |
Bangkok, Thailand |
| Date |
12-17 June 2022 |
| Publisher |
JACoW Publishing, Geneva, Switzerland |
| Editorial Board |
Frank Zimmermann (CERN, Meyrin, Switzerland); Hitoshi Tanaka (RIKEN, Hyogo, Japan); Porntip Sudmuang (SRLI, Nakhon, Thailand); Prapong Klysubun (SRLI, Nakhon, Thailand); Prapaiwan Sunwong (SRLI, Nakhon, Thailand); Thakonwat Chanwattana (SRLI, Nakhon, Thailand); Christine Petit-Jean-Genaz (CERN, Meyrin, Switzerland); Volker R.W. Schaa (GSI, Darmstadt, Germany) |
| Online ISBN |
978-3-95450-227-1 |
| Online ISSN |
2673-5490 |
| Received |
09 June 2022 |
| Revised |
15 June 2022 |
| Accepted |
15 June 2022 |
| Issue Date |
03 July 2022 |
| DOI |
doi:10.18429/JACoW-IPAC2022-THPOMS035 |
| Pages |
3038-3040 |
| Copyright |
 Published by JACoW Publishing under the terms of the Creative Commons Attribution 3.0 International license. Any further distribution of this work must maintain attribution to the author(s), the published article's title, publisher, and DOI. |
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