Efficacy of fine needle aspiration cytology in the early diagnosis of different head and neck malignancies: a hospital based prospective study

Authors

  • Bonapart Chowdhury Department of ENT, Shri Ramkrishna Institute of Medical Sciences and Sanaka Hospitals, Malandighi, Durgapur, West Bengal, India

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20200626

Keywords:

FNAC, Sensitivity, Specificity, Head and neck, Tumour

Abstract

Background: Fine needle aspiration cytology (FNAC) is a very useful diagnostic modality for early diagnosis of cancers in the head and neck region where large majority of the lesions are in the form of cervical lymphadenopathy, thus FNAC is easily feasible. This can be used as a significant screening tool if sensitivity is found to be high.

Methods: A hospital based prospective study to find the accuracy of FNAC in correctly diagnosing malignant lesions in patients with visible or palpable mass lesions in the head and neck area where both FNAC and histopathological examination (HPE) is possible taking HPE as gold standard.  

Results: FNAC is a very effective tool in the early diagnosis of different head and neck malignancies with sensitivity of 91.37% and specificity of 97.62%.

Conclusions: FNAC is a simple, quick and safe diagnostic modality for different head and neck malignancies with significant sensitivity and specificity, thus can be used as a screening tool effectively. 

Author Biography

Bonapart Chowdhury, Department of ENT, Shri Ramkrishna Institute of Medical Sciences and Sanaka Hospitals, Malandighi, Durgapur, West Bengal, India

Assistant Professor and HOD, Department Of ENT

References

Bhattacharjee A, Chakraborty A, Purkaystha P. Prevalence of head and neck cancers in the North East- an institutional study: Indian J Otolaryngol Head Neck Surg. 2006;58:15-9.

Thakur S, Chaturvedi V, Singh AK, Puttewar MP, Raizada RM. Pattern of ear, Nose, pharynx, larynx and esophagus (ENPLO) cancers in rural based hospital. Indian J Otolaryngol Head Neck Surg. 2001;53:93-9.

McGuirt WF. Differential diagnosis of neck masses. In: Cummings Ch W, Fredrickson JM, editors. Otolaryngology head & neck surgery, vol 3. 3rd ed. Philadelphia (PA) : Mosby; 1998: 1743-1746.

Kim BM, Kim EK, Kim MJ, Yang WI, Park CS. Sonographically guided core needle biopsy of cervical lymphadenopathy in patients without known malignancy. J Ultrasound Med. 2007;26:585-91.

Nada al Alwan, Al Hashimi AS, Salman MM, Al Attar EA. Fine needle aspiration cytology versus histopathology in diagnosing lymph node lesion. Eastern Mediterranean Health J. 1996;2:320-5.

Jacobs JC, Katz RL, Shabb N, el-Naggar A, Ordonez NG, Pugh W. Fine needle aspiration of lymphoblastic lymphoma- A multiparametre diagnostic approach. Acta Cytol. 1992;36:887-94.

Wakely PE Jr, Kornstein MJ. Cytopathology of lymphoblastic lymphoma & Leukaemia:The MCV experience. Pediatr Patol Lab Med. 1996;16:243-52.

Martin HE, Ellis EB. Biopsy by needle puncture and aspiration. Ann Surg. 1930;92:169-81.

Morris LF, Ragavendra N, Yeh MW. Evidence-based assessment of the role of ultrasonography in the management of benign thyroid nodules. World J Surg. 2008;32:1253-63.

Gharib H. Fine-needle aspiration biopsy of thyroid nodules:Advantages, limitations, and effect. Mayo Clin Proc. 1994;69:44-9.

Castro MR, Gharib H. Thyroid fine-needle aspiration biopsy:Progress, practice, and pitfalls. Endocr Pract. 2003;9:128-36.

Gharib H, Goellner JR. Fine-needle aspiration biopsy of thyroid nodules. Endocr Pract. 1995;1:410-7.

Jeffrey PB, Miller TR. Fine-needle aspiration cytology of the thyroid. Pathology (Phila). 1996;4:319-35.

Moon HG, Jung EJ, Park ST, Ha WS, Choi SK, Hong SC, et al. Role of ultrasonography in predicting malignancy in patients with thyroid nodules. World J Surg. 2007;31:1410-6.

Cappelli C, Castellano M, Pirola I, Cumetti D, Agosti B, Gandossi E, et al. The predictive value of US findings in the management of thyroid nodules. QJM. 2006;100:29-35.

Dwarakanathan AA, Staren ED, D’Amore MJ, Kluskens LF, Martirano M, Economou SG. Importance of repeat fine-needle biopsy in the management of thyroid nodules. Am J Surg. 1993;166:350-2.

Howlett DC, Harper B, Quante M, Berresford A, Morley M, Grant J, et al. Diagnostic adequacy and accuracy of fine needle aspiration cytology in neck lump assessment: results from a regional cancer network over a one year period. J Laryngol Otol. 2007;121:571-9.

Kopald KH, Layfield LJ, Mohrmann R, Foshaq LJ, Giuliano AE. Clarifying the role of fine-needle aspiration cytologic evaluation and frozen section examination in the operative management of thyroid cancer. Arch Surg. 1989;124:1201-5.

Cohen MB, Reznicek MJ, Miller TR. Fine needle aspiration biopsy of the salivary glands. Pathol Annu. 1992;27:213-45.

Al-Khafaji BM, Nestok BR, Katz RL. Fine needle aspiration of 154 parotid masses with histologic correlation:ten year experience at the University of Texax M.D.Anderson cancer center. Cancer. 1998;84:153-9.

Wong DSY, Li GKH. The role of fine needle aspiration cytology in the management of parotid tumors:a critical clinical appraisal. Head Neck. 2000;22:469-73.

Hee CGQ, Perry CF. Fine needle aspiration cytology of parotid tumors:is it useful? ANZ J Surg. 2001;71:345-8.

Zhang S, Bao R, Bagby J, Abreo F. Fine needle aspiration of salivary glands: 5-year experience from a single academic center. Acta Cytol. 2009;53(4):375-82.

Downloads

Published

2020-02-24

Issue

Section

Original Research Articles