This study aims to review the literacy-related articles published in the journal, Modern English Education, in commemoration of its 20 years of history from 2000 to 2019. A total of 182 literacy-related papers (27.62%) out of 659 articles have been published over the past twenty years. These were reviewed in terms of three perspectives: main research themes, the subjects’ levels of proficiency, and research methodology. This study revealed that the research on reading has been productive in the area of teacher and learner traits, and vocabulary teaching and learning whereas the research on writing has been fertile in the field of text analysis and teacher and learner traits. This review indicated that more research related assessment and technology use is required in the future. In addition, this review showed that the subjects were skewed, and studies were mostly conducted at the college level. Therefore, the future research should balance the subjects’ levels more. As for research methodology, the articles displayed a heavy reliance on quantitative methods, requiring more qualitative research and integration of qualitative and quantitative research in the future.