Paper Titles

Change in Energy and Entropy of the Non-Spinning Black Holes
p.12

Extractive Spectrophotometric Determination of Pd(II) with Sodium Salt of Hexamethyleneiminecarbodithioate
p.20

Observations of Different Type of Bursts Associated with M 6.3 Solar Flares
p.29

Effect of Annealing Temperature on the Optical Properties of ZnO Nanoparticles
p.37

Spectral Correlation Analysis and Antimicrobial Activities of some 2,4-Dimethoxy Phenyl Chalcones
p.48

Insect Antifeedant Potent Unsaturated 1,3-Oxazine-2-Amines
p.66

Aryl Chalcones as Efficient Precursors for Deriving Oxazine: Solvent-Free Synthesis and Antimicrobial Activities of some Oxazine-2-amines
p.82

Magnetic Fields for Electropolishing Improvement: Materials and Systems
p.98

IR and NMR Spectral Studies of Some 4-(6-methoxy-2-naphthyl)-5,6-dihydro-6-(Substituted Phenyl)-⁴H-1,3-Oxazine-2-Amines: Assessment of Substituent
p.109

HomeInternational Letters of Chemistry, Physics and...International Letters of Chemistry, Physics and...Spectral Correlation Analysis and Antimicrobial...

Spectral Correlation Analysis and Antimicrobial Activities of some 2,4-Dimethoxy Phenyl Chalcones

Article Preview

Abstract:

A series of 2,4-dimethoxy phenyl chalcones have been synthesized by Crossed-Aldol condensation of 2,4-dimethoxy phenyl and various substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.

By email Full Text Pdf

Info:

Periodical:

International Letters of Chemistry, Physics and Astronomy (Volume 23)

Pages:

48-65

DOI:

https://doi.org/10.56431/p-26s6na

Citation:

Cite this paper

Online since:

November 2013

Authors:

S. John Joseph, R. Arulkumaran, D. Kamalakkannan, S.P. Sakthinathan, R. Sundararajan, R. Suresh, S. Vijayakumar, K. Ranganathan, N. Kalyanasundaram, Ganesan Vanangamudi*, Ganesamoorthy Thirunarayanan

Keywords:

Antimicrobial Activities, IR Spectra, NMR Spectra, Substituent Effects, Substituted Styryl 2,4-Dimethoxy Phenyl Ketones, UV Spectra

Export:

RIS, BibTeX

Permissions:

Creative Commons CC BY 4.0

* - Corresponding Author

[1] Thirunarayanan G., Vanangamudi G., Subramanian M., Organic Chem: An Indian J. 9(1) (2013) 1-16.

[2] Janaki P., Sekar K. G., Thirunarayanan G., J. Saudi Chem. Soc. 2013, Accepted and in press. DOI: org/.

DOI: 10.1016/j.jscs.2012.11.013

[3] Holla B. S., Akberali P. M., Shivananda M. K., IL Farmaco 55 (2000) 256-261.

DOI: 10.1016/s0014-827x(00)00030-6

[4] Venkat Reddy G., Maitraie D., Narsaiah B., Rambabu Y., ShanthanRao P., Synth. Commun 31(18) (2004) 2882-2884.

[5] Orsini F., Sello G., Fumagalli T., Synlett. (2006), 1717-1718.

[6] Vanangamudi G., Subramanian S., Jayanthi P., Arulkumaran R., Kamalakkannan D., Thirunarayanan G., Arab. J. Chem., 201.

DOI: 10.1016/j.arabjc.2010.07.019

[7] Tran T. D., Park H., Ecker G. F., Thai K. M., 2,3'-Hydroxychalcone Analogues: Synthesis and Structure-PGE2 Inhibitory Activity Relationship, 12th International Electronic Conference on Synthetic Organic Chemistry (ECSOC-12) 1-30 November 2008; http://www.usc.es/congresos/ecsoc/12/ECSOC12.htm &http://www.mdpi.org/ecsoc-12 No. C0011, pp.1-7.

DOI: 10.3390/ecsoc-12-01247

[8] Mohan S. B., Behera T. P., Ravi Kumar B. V. V., Int. J. ChemTech. Res. 2(3) 2010 1634-1637.

[9] Thirunarayanan G., Vanangamudi G., Arkivoc. 12 (2006) 58-64.

[10] Thirunarayanan G., Ananthakrishna Nadar P., J. Indian Chem. Soc. 83(11) (2006) 1107-1112.

[11] Ballini R., Bosica G., Maggi R., Ricciutelli M., Righi P., Sartori G., Sartorio R., Green Chem. 3 (2001) 178-180.

DOI: 10.1039/b101355f

[12] Solhy A., Tahir R., Sebti S. Skouta R., Bousmina M., Zahouily M., Larzek M., Appl. Catal. A: General. 374 (2010) 189-193.

DOI: 10.1016/j.apcata.2009.12.008

[13] Thirunarayanan G., J. Indian Chem. Soc. 84 (2008) 447-451.

[14] Basaif S. A., Sobahi T. R., Khalil A. K., Hassan M. A., Bulletin of the Korean Chem. Soc. 26(11) (2005) 1677-1681.

[15] Xu Q., Yang Z., Yin D., Zhang F., Catal. Commun. 9(1) (2008) 1579-1582.

[16] Kumar P., Kumar S., Husain K., Kumar A., Bioorg. Med. Chem. 18(14) (2010) 4965-4974.

[17] Zhang Z., Dong Y., W., Wang G. W., Chem. Lett. 32(10) (2003) 966-967.

[18] Thirunarayanan G., IUP. J. Chem. 3(4) (2010) 35-54.

[19] Thirunarayanan G., et al., Elixir Org. Chem. 45 (2012) 7898-7905.

[20] Thirunarayanan G., Mayavel P., Thirumurthy K., Spectrochimica Acta. 91A (2012) 18-22.

[21] Sundararajan R., et al., Int. J. Pharm. Chem. Sci. 1(4) (2012) 1657-1677.

[22] Thirunarayanan G., Surya S., Srinivasan S., Vanangamudi G., Sathiyendiran V., Spectrochim. Acta. 75A (2010) 152-156.

[23] Janaki P., Sekar K. G., Thirunarayanan G., Org. Chem: An Indian J. 9(2) (2013) 68-80.

[24] Arulkumaran R., Vijayakumar S., Sundararajan R., Sakthinathan S. P., Kamalakkannan D., Suresh R., Ranganathan K., Vanangamudi G., Thirunarayanan G., International Letters of Chemistry, Physics and Astronomy 4 (2012) 17-38.

DOI: 10.56431/p-6ilr3n

[25] Kamalakkannan D, Vanangamudi G, Arulkumaran R, Thirumurthy K, Mayavel P, Thirunarayanan G, Elixir Org. Chem., 46, 2012, 8157-8166.

[26] Sivakumar M., PhrabuSreeneivasan S., Kumar V., Doble M., Bioorg. Med Chem. Lett. 17(10) (2007) 3169-3172.

[27] Liu X., Go M. L., Bioorg. Med.Chem. 14(1) (2006) 153-163.

[28] Arulkumaran R, et al., IUP J. Chem. 3(1) (2010) 82-98.

[29] Deng J., Sanchez T., Lalith Q. A. M., Bioorg. Med. Chem. 15(14) (2007) 4985-5002.

[30] Bauer A. W., Kirby W. M. M., Sherris J. C., Truck M., Am. J. Clin. Pathol. 45 (1966) 493-496.

[31] Thirunarayanan G., "Fly-ash: H2O Assisted Aldol Condensation: Effect of Solvents on the Synthesis of Some Aryl (E) 2-propen-1-ones" Accepted article in Annales, UMCS Chem. J., 2013.

DOI: 10.2478/v10063-012-0004-7

[32] Marquardt F. H., Helv. Chim. Acta. 48 (7) (1965) 1476-1485.

[33] Liu Xiaoling, Bioorg. Med. Chem. 14(1) (2006) 153-163.

[34] Buu-Hoi Ng. Ph., J. Org. Chem. 22 (1957) 193-7.

[35] Vandrewala H. P., J. Univ. Bom Sci: Phys Sci, Math, Biol. Sci. Med. 16 (1948) 43-5.

[36] Kauffmann Hugo, Ber. Dtsch. Chem. Ges. 54B (1921) 795-802.

[37] Swain C. G., Lupton Jr. E. C., J. Am. Chem. Soc. 90(16) (1968) 4328-4337.

[38] Deiva C. M., Pappano N. B., Debattisata N. B., Rev. Microbiol. 29(4) (1998) 307-310.

[39] Thirunarayanan G., J. Saudi Chem. Soc., 2011.

DOI: 10.1016/j.jscs.2011.12.003

[40] K. Ranganathan, R. Suresh, D. Kamalakkannan, R. Arulkumaran, R. Sundararajan, S. P. Sakthinathan, S. Vijayakumar, G. Vanangamudi, K. Thirumurthy, P. Mayavel, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 4 (2012) 66-75.

DOI: 10.56431/p-jjf25v

[41] R. Arulkumaran, S. Vijayakumar, R. Sundararajan, S. P. Sakthinathan, D. Kamalakkannan, R. Suresh, K. Ranganathan, P. R. Rajakumar, G. Vanangamudi, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 5 (2013) 21-38.

DOI: 10.18052/www.scipress.com/ilcpa.10.21

[42] S. Vijayakumar, R. Arulkumaran, R. Sundararajan, S. P. Sakthinathan, R. Suresh, D. Kamalakkannan, K. Ranganathan, K. Sathiyamoorthy, V. Mala, G. Vanangamudi, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 9(1) (2013) 68-86.

DOI: 10.56431/p-v23467

[43] Thirunarayanan G., Sekar K. G., International Letters of Chemistry, Physics and Astronomy 10 (2013) 18-34.

[44] R. Sundararajan, R. Arulkumaran, S. Vijayakumar, D. Kamalakkannan, R. Suresh, S. John Joseph, K. Ranganathan, S. P. Sakthinathan, G. Vanangamudi, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 1 (2014) 67-73. (Received 23 November 2013; accepted 28 November 2013)

DOI: 10.18052/www.scipress.com/ilcpa.20.67