Insect Antifeedant Potent Halogen Substituted Phenyl Chalcones

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Abstract:

Some 2′,3′,4′-trichlorophenyl chalcones [(E)-1-(2,3,4-trichlorophenyl)-3-(substituted phenyl)-2-propen-1-ones] have been synthesised using sulfated Titania catalyzed solvent-free aldol condensation between 2,3,4-trichloroacetophenone and substituted benzaldehydes. The purities of synthesised chalcones were checked by their analytical, physical and spectroscopic data reported in literature. The insect antifeedant activities of these chalcones have been studied using 4th instar larvae Achoea Janata L by castor leaf disc bio-assay method. The chloro substituted chalcones shows significant insect antifeedant activity.

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67-73

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October 2013

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[1] Mirinda C. L., Aponso G. L., Stevens J. F., Pure Appl Chem 73 (2000) 1197-1208.

Google Scholar

[2] Monostory K., Tamasi V., Vereckey L., Perjesi P., Toxicol 184 (2003) 203-210.

Google Scholar

[3] Subramanian M., Vanangamudi G., Thirunarayanan G., Spectrochim Acta. 110A (2013) 116-123.

Google Scholar

[4] Modzelewska A., Pettit C., Achanta G., Davidson N. E., Huang P., Khan R. K., Bioorg Med Chem 14 (2006) 3491-3495.

Google Scholar

[5] Ahmad A. L., Dowsett A. B., Tyrrell D. A., Antiviral Res. 8 (1987) 27-39.

Google Scholar

[6] Liu M., Wilairat M. L., Croft, S. L., Tan A. L. C., Go M., Bioorg Med Chem. 11 (2003) 2729-2738.

Google Scholar

[7] Weber W. M., Hunsaker L. A., Abcouwer S. F., Deck L. M., Jagt D. L. V., Bioorg Med Chem. 13 (2005) 3811-3820.

Google Scholar

[8] Liu X., Go M. L., Bioorg Med Chem. 14 (2006) 153-163.

Google Scholar

[9] Deng J., Sanchez T., Lalith Q. A. M., Dayam R., Yunes R. A., Garofalo A., et al. Bioorg Med Chem. 15 (2007) 4985-5002.

Google Scholar

[10] Lin Y. M., Zhou Y., Flavin M. T., Zhou L. M., Nie W., Che F. C., Bioorg Med Chem. 10 (2002) 2795-2802

Google Scholar

[11] Arulkumaran R., Sundararajan R., Vanangamudi G., Subramanian M., Ravi K., Sathiyendiran V. et al.. Iup J Chem. 3 (2010) 82-98.

Google Scholar

[12] Kotra V., Ganapathy S., Adapa S. R., Indian J Chem 49B (2010) 1109-1116.

Google Scholar

[13] Reichwald C., Shimony O., Sierra N. S., Jaffe C. L., Kunick C., J Med Chem. 51 (2008) 659-665.

Google Scholar

[14] Said M. M., Ahmed A. A. E., Alfy A. T. E., Arch Pharm Res. 27 (2004) 1194-1201.

Google Scholar

[15] Bhat B. A., Dhar K. L., Puri A. K., Saxena A. K., Shanmugavel M., Quazi G. N., Bioorg Med.Chem. 15 (2005) 3177-3180.

Google Scholar

[16] Tragar W., Jenson J. B., Science. 193 (1976) 673-675.

Google Scholar

[17] Nem N. H., Kim. Y., You Y. J., Hong D. H., Kim H. M., Ahn B. Z., Eur J Med Chem. 38(2) (2003) 179-187.

Google Scholar

[18] Pushkar N. K., Balawant S. J., Alternative Medicine: Herbal Drugs and their Critical appraisal - Part II", Progress in Drug Research. 2001; 57: (E. Jucker, Ed.) Birkhäuser Verlag, Basel (Switzerland).

Google Scholar

[19] Oyedapo A. O., Mankanju V. O., Adewunmi C. O., Iwalewa E. O., Adenowo T. K., Afr J Trad CAM. 1 (2004) 55-62.

Google Scholar

[20] Suryawashni S. N., Chandra N., Kumar P., Porwal J., Gupta S., Eur J Med Chem. 43 (2008) 2473-2478.

Google Scholar

[21] Blickenstaff R.T., Hanson W. R., Reddy S., Witt R., Bioorg Med Chem. 3 (1995) 917-922.

Google Scholar

[22] Thirunarayanan G., Surya S., Srinivasan, S., Vanangamudi G., Sathiyendiran V., Spectrochim Acta. 75A (2010) 152-156.

Google Scholar

[23] Fouda A. S., Shafie A. A. E., Gadow H. S., Portugaliae Electrochim Acta. 20 (2002) 13-23.

Google Scholar

[24] Sekar K. G., Thirunarayanan G., Int J Sci Res Know. 1 (2013) 299-307.

Google Scholar

[25] Thirunarayanan G., Asian J Chem. 15 (2003) 907-910.

Google Scholar

[26] Dasharathi D., Netaji R., Basheer M. A.,Vibhute Y. B., Ultra Science. 17 (2005) 89-92.

Google Scholar

[27] Nalwar Y. S., Sayyed M. A., Mokle S. S., Zanwar P, R., Vibhute Y. B., World J. Chem. 4(2009)123-126.

Google Scholar

[28] Thirunarayanan G., J Indian Chem Soc. 85(2008)447-451.

Google Scholar

[29] Janaki P., Sekar K. G., Thirunarayanan G., J Saudi Chem Soc. (2012). Doi:org.

DOI: 10.1016/j.jscs.2012.11.013

Google Scholar

[30] Thirunarayanan G., Thirumurthy K., Vanangamudi G., Subramanian M., Arulkumaran R., Kamalakkannan D. et al. Elixir Org Chem. 45 (2012) 7898-7905.

Google Scholar

[31] Thirunarayanan G., J Saudi Chem Soc. (2011).

DOI: 10.1016/j.jscs.2011.12.003

Google Scholar

[32] Thirunarayanan G., J Saudi Chem Soc. (2011).

DOI: 10.1016/j.jscs.2011.10.011

Google Scholar

[33] Krishnakumar B., Velmurugan R., Swaminathan M., Catal Commun. 12 (2011) 375-379.

Google Scholar

[34] Sundararajan R., Arulkumaran R., Vijayakumar S., Kamalakkannan D., Suresh R., John Joseph S., Ranganathan K., Vanangamudi G., Subramanian M., Thirunarayanan G., Muthuvel I., Krishnakumar B., Q-Science Connect. 2013

DOI: 10.5339/connect.2013.30

Google Scholar

[35] Hoong-Kun F., Yeap C. S., Jagadeesh Prasad D., Nayak S. P., Laxmana K., Acta Cryst Sec E 67 (2011) o241.

Google Scholar

[36] Dethler V. G., Chemical insect attractants and Repellants. Blackistan, Philadeciphia, p.210. (1947).

Google Scholar

[37] R. Arulkumaran, S. Vijayakumar, R. Sundararajan, S. P. Sakthinathan, D. Kamalakkannan, R. Suresh, K. Ranganathan, G. Vanangamudi, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 4 (2012) 17-38.

DOI: 10.56431/p-6ilr3n

Google Scholar

[38] K. Ranganathan, R. Suresh, D. Kamalakkannan, R. Arulkumaran, R. Sundararajan, S. P. Sakthinathan, S. Vijayakumar, G. Vanangamudi, K. Thirumurthy, P. Mayavel, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 4 (2012) 66-75.

DOI: 10.56431/p-jjf25v

Google Scholar

[39] R. Arulkumaran, S. Vijayakumar, R. Sundararajan, S. P. Sakthinathan, D. Kamalakkannan, R. Suresh, K. Ranganathan, P. R. Rajakumar, G. Vanangamudi, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 5 (2013) 21-38.

DOI: 10.18052/www.scipress.com/ilcpa.10.21

Google Scholar

[40] S. Vijayakumar, R. Arulkumaran, R. Sundararajan, S. P. Sakthinathan, R. Suresh, D. Kamalakkannan, K. Ranganathan, K. Sathiyamoorthy, V. Mala, G. Vanangamudi, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 9(1) (2013) 68-86.

DOI: 10.56431/p-v23467

Google Scholar

[41] Thirunarayanan G., Sekar K. G., International Letters of Chemistry, Physics and Astronomy 10 (2013) 18-34. ( Received 03 October 2013; accepted 07 October 2013 )

Google Scholar