Annals of Nuclear Cardiology
Online ISSN : 2424-1741
Print ISSN : 2189-3926
ISSN-L : 2189-3926
Cardiac Sarcoidosis - From the CME Session at 63rd SNMMI Annual Meeting
Qualitative and Quantitative Assessments of Cardiac Sarcoidosis Using 18F-FDG PET
Osamu ManabeHiroshi OhiraKeiichiro YoshinagaMasanao NayaNoriko Oyama-ManabeNagara Tamaki
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2017 Volume 3 Issue 1 Pages 117-120

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Abstract

Sarcoidosis is a multisystem disease pathologically characterized by non-caseating granuloma. Cardiac sarcoidosis (CS) remains an important prognostic factor of sarcoidosis patients. 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) has been applied as a noninvasive tool not only for CS diagnoses but also for the evaluation of therapeutic effects and prognoses. Visual assessment is a standard method to evaluate whether the 18F-FDG uptake is physiological or active inflammation due to the CS. A semi-quantitative assessment using the standardized uptake value (SUV) is a simple method for achieving a more accurate diagnosis. A volume-based analysis has been proposed as a new marker that can provide information about the improvement or prevention of heart failure and can be used to predict a further clinical event in CS patients. This is a brief review of the objective and quantitative assessments of the magnitude and extent of CS activity with the use of 18F-FDG PET.

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© The Japanese Society of Nuclear Cardiology 2017
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