A Suspected Case of Hyperkeratotic Head and Neck Malassezia Dermatosis Presenting with Acanthosis Nigricans

@article{ART002424106},
author={ 안민균 and 윤지하 and 조은별 and 박은주 and 김광호 },
title={A Suspected Case of Hyperkeratotic Head and Neck Malassezia Dermatosis Presenting with Acanthosis Nigricans},
journal={대한의진균학회지},
issn={1226-4709},
year={2018},
volume={23},
number={4},
pages={111-114},
doi={10.17966/jmi.2018.23.4.111},
url={http://dx.doi.org/10.17966/jmi.2018.23.4.111}

TY - JOUR
AU - 안민균
AU - 윤지하
AU - 조은별
AU - 박은주
AU - 김광호
TI - A Suspected Case of Hyperkeratotic Head and Neck Malassezia Dermatosis Presenting with Acanthosis Nigricans
T2 - 대한의진균학회지
PY - 2018
VL - 23
IS - 4
PB - 대한의진균학회
SP - 111-114
SN - 1226-4709
AB - A 19-year-old woman presented with an asymptomatic cutaneous discoloration on her nape. Dermatological examination revealed localized dark brown to dark pigmented velvety macules and patches. She denied a past medical history, except for a 7-kg weight gain over a 6-months period. Histopathologically, the specimen showed hyperkeratosis, epidermal hyperplasia, mild acanthosis, and papillomatosis. In addition, keratin material and fungal spore were noted between the papilloma ridges. Periodic acid-Schiff special stain showed a positive result for the fungal spore in the horny layer. She was treated with a daily oral dose of terbinafine and topical flutrimazole. After 12 weeks of treatment, she is currently under observation without pigmentation and adverse effect. We considered the initial diagnosis as acanthosis nigricans because of weight gain, similar clinical features, and histological findings. However, the final diagnosis was hyperkeratotic head and neck Malassezia dermatosis considering the presence of yeast and the dramatic improvement after antifungal treatment. To the best of our knowledge, hyperkeratotic head and neck Malassezia dermatosis is not well characterized in the literature. It is an unusual variant of pityriasis versicolor. The skin lesion appears brown to dark, scaly, and hyperkeratotic macules and patches located on the face and neck. Here, we reported an unusual case of hyperkeratotic head and neck Malassezia dermatosis.
KW - Acanthosis nigricans, Fungal spore, Hyperkeratotic head and neck Malassezia dermatosis, Malassezia species
DO - 10.17966/jmi.2018.23.4.111
UR - http://dx.doi.org/10.17966/jmi.2018.23.4.111
ER -

안민균 , 윤지하 , 조은별 , 박은주 and 김광호 (2018). A Suspected Case of Hyperkeratotic Head and Neck Malassezia Dermatosis Presenting with Acanthosis Nigricans. 대한의진균학회지, 23( 4), 111- 114.

안민균 , 윤지하 , 조은별 , 박은주 and 김광호 . 2018, “A Suspected Case of Hyperkeratotic Head and Neck Malassezia Dermatosis Presenting with Acanthosis Nigricans”, 대한의진균학회지, vol. 23, no. 4, pp. 111-114. Available from: doi:10.17966/jmi.2018.23.4.111

안민균 윤지하 et al. 조은별 박은주 김광호 “A Suspected Case of Hyperkeratotic Head and Neck Malassezia Dermatosis Presenting with Acanthosis Nigricans” 대한의진균학회지 23.4 pp. 111-114 (2018): 111.

안민균 , 윤지하 , 조은별 , 박은주 , 김광호 . A Suspected Case of Hyperkeratotic Head and Neck Malassezia Dermatosis Presenting with Acanthosis Nigricans 대한의진균학회지 [Internet]. 2018; 23( 4), : 111-114. Available from: doi:10.17966/jmi.2018.23.4.111

안민균 , 윤지하 , 조은별 , 박은주 and 김광호 . “A Suspected Case of Hyperkeratotic Head and Neck Malassezia Dermatosis Presenting with Acanthosis Nigricans” 대한의진균학회지 23, no.4 (2018): 111-114. doi: 10.17966/jmi.2018.23.4.111

홈 권호 목록 논문 목록 논문 상세

A Suspected Case of Hyperkeratotic Head and Neck Malassezia Dermatosis Presenting with Acanthosis Nigricans

대한의진균학회지

약어 : 의진균지

2018, vol.23, no.4, pp.111 - 114

DOI : 10.17966/jmi.2018.23.4.111

발행기관 : 대한의진균학회

연구분야 : 미생물학

안민균¹ , 윤지하² , 조은별³ , 박은주⁴ , 김광호⁵

¹한림대학교 피부과

²한림대학교 의과대학 피부과학교실

³한림대학교 의과대학

⁴한림대학교

⁵한림대학교

인용한 논문 수 : 1 서지 간략 보기

초록

A 19-year-old woman presented with an asymptomatic cutaneous discoloration on her nape. Dermatological examination revealed localized dark brown to dark pigmented velvety macules and patches. She denied a past medical history, except for a 7-kg weight gain over a 6-months period. Histopathologically, the specimen showed hyperkeratosis, epidermal hyperplasia, mild acanthosis, and papillomatosis. In addition, keratin material and fungal spore were noted between the papilloma ridges. Periodic acid-Schiff special stain showed a positive result for the fungal spore in the horny layer. She was treated with a daily oral dose of terbinafine and topical flutrimazole. After 12 weeks of treatment, she is currently under observation without pigmentation and adverse effect. We considered the initial diagnosis as acanthosis nigricans because of weight gain, similar clinical features, and histological findings. However, the final diagnosis was hyperkeratotic head and neck Malassezia dermatosis considering the presence of yeast and the dramatic improvement after antifungal treatment. To the best of our knowledge, hyperkeratotic head and neck Malassezia dermatosis is not well characterized in the literature. It is an unusual variant of pityriasis versicolor. The skin lesion appears brown to dark, scaly, and hyperkeratotic macules and patches located on the face and neck. Here, we reported an unusual case of hyperkeratotic head and neck Malassezia dermatosis.

키워드

Acanthosis nigricans, Fungal spore, Hyperkeratotic head and neck Malassezia dermatosis, Malassezia species

참고문헌(10)

[학술지] Boralevi F / 2006 / Hyperkeratotic head and neck Malassezia dermatosis / Dermatology 212 : 36 ~ 40
[학술지] Sinha S / 2007 / Juvenile acanthosis nigricans / J Am Acad Dermatol 57 : 502 ~ 508
[학술지] Pham-Ledard A / 2010 / Facial confluent and reticulate papillomatosis (Gougerot-Carteaud syndrome) or hyperkeratotic head and neck Malassezia dermatitis? / Ann Dermatol Venereol 137 : 451 ~ 454
[단행본] Elder DE / 2014 / Lever's histopathology of the skin / Lippincott Williams & Wilkins : 732
[학술지] Park YJ / 2015 / Differentiating confluent and reticulated papillomatosis from acanthosis nigricans / J Cutan Pathol 42 : 944 ~ 952
[학술지] Tamraz H / 2013 / Confluent and reticulated papillomatosis: clinical and histopathological study of 10 cases from Lebanon / J Eur Dermatol Venereol 27 : e119 ~ e123
[학술지] Cutsem JV / 1991 / The antiiflammatory effects of ketoconazole / J Am Acad Dermatol 25 : 257 ~ 261
[학술지] Nickoloff BJ / 1988 / Further characterization of the keratinocyte somatomedin-C/insulin-like growth factor I(SM-C/IGF-I)receptor and the biological responsiveness of cultured keratinocytes to SM-C/IGF-I / Dermatologica 177 : 265 ~ 273
[학술지] Faergemann J. / 2001 / Treatment of seborrhoeic dermatitis with oral terbinafine? / Lancet 358 : 170
[학술지] Merlos M / 1996 / Topical anti-inflammatory properties of flutrimazole, a new imidazole antifungal agent / Infalmm Res 45 : 20 ~ 25