Dataset on cadaveric human abdominal aorta aneurysm biomechanics (uniaxial) and histology
Description
The present dataset is a collection of information about the biomechanical behavior and histological characterization of abdominal aortic aneurysms (AAA) harvested during the autopsy procedure. The primary hypothesis of the present research is: Do cadaveric AAA walls, when previously stressed by inflation, conserve significant resistance against tearing comparable to no previously stressed aortas described in the literature? Eight AAAs (6 fusiform and two saccular) were carefully dissected and had their branches ligated with cotton or prolene sutures. Each specimen has been submitted to intraluminal pressurization, up to the rupture of their wall. This pressurization was made through the inflation of an air balloon inside the specimens up to their rupture. Four samples were collected from each specimen (two from each side of the rupture border and two control samples, one from a proximal and a second from a distal no dilated region of the vessel) for uniaxial tensile tests and histological analysis. The uniaxial tensile test utilized the INSTRON SPEC 2200 device and was coordinated by INSPEC software and SERIES IX software. The variables measured through this test were failure stress, failure tension, and failure strain. Each sample test generated a chart representing the relationship between stress and strain. The histological analysis included Picrosirius (collagen fibers) and Voerhoeff (elastic fibers) stains. Unfortunately, some samples were lost, especially during histological processing. A quantitative analysis (collagen and elastic fibers) was made using the software Pannoramic Viewer/Case Viewer.1 Notable findings: Even after being stretched/stressed up to their rupture, the specimens conserved uniaxial biomechanical properties comparable to AAA and normal aorta samples previously described in the literature by Monteiro e Nynomiya respectively.2,3 DATA DESCRIPTION: a) Biomechanical Data: For each valid sample test, three documents are generated: 1. Stress X strain chart 2. Table (excel file containing all the values related to the stress X strain chart 3. A report from the Biomechanical test software containing details of the test All charts contain a notification in their left upper corner about the failure stress, strain and tension of each sample. It is important to highlight here that some samples did not produce valid biomechanical tests, so they do not have their results included here. b) Histological Data: The percentage of coverage of collagen fibers and elastin fibers is expressed in table I in decimal numbers (for example, 0.36 = 36%). Similarly to the sampling for biomechanical tests, four samples were harvested from each aorta, when it was feasible. Each case has a "histology files" folder containing the images (.JPG) used for the analysis. Ps.: Case C samples (histology) were damaged during processing (therefore they were not included in the present dataset).