Vet Med - Czech, 2020, 65(7):320-326 | DOI: 10.17221/76/2019-VETMED

Tetralogy of Fallot with right ventricular outflow tract obstruction and patent ductus arteriosus in a dogCase Report

S Park1, MJC Ang2, MD Kittleson3, KO Cho2, J Choi1
1 Veterinary Medical Imaging, College of Veterinary Medicine and BK 21 Plus Project Team, Chonnam National University, Yongbong-ro, Buk-gu, Gwangju, Republic of Korea
2 Laboratory of Veterinary Pathology, College of Veterinary Medicine and BK 21 Plus Project Team, College of Veterinary Medicine, Chonnam National University, Yongbong-ro, Buk-gu, Gwangju, Republic of Korea
3 Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California Davis, Davis, CA

In this study we describe the echocardiographic features of a complex cardiac defect with a right to left shunt through tetralogy of Fallot and also a left to right shunt through a patent ductus arteriosus (PDA) in a 3-year-old dog. The echocardiography revealed a tetralogy of Fallot with a severely hypertrophied right ventricular outflow tract (RVOT), and a left to right shunting PDA. A contrast echocardiogram showed microbubbles moving from the right ventricle to the aorta through the ventricular septal defect. They then reached the main pulmonary artery through the PDA rather than through the RVOT. The necropsy confirmed tetralogy of Fallot with an RVOT obstruction and a PDA. This patient could have maintained the pulmonary circulation through the PDA in the spite of the right ventricular outflow tract obstruction and survive a long period. Not only the echocardiography, but also the contrast echocardiogram using agitated saline and trans-sectional images in CT enhanced the comprehensive understanding of the anatomic defects in this complex cardiac defect.

Keywords: canine; computed tomography; contrast echocardiogram

Received: June 21, 2019; Accepted: May 24, 2020; Published: July 31, 2020  Show citation

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Park S, Ang M, Kittleson M, Cho K, Choi J. Tetralogy of Fallot with right ventricular outflow tract obstruction and patent ductus arteriosus in a dog. Vet Med-Czech. 2020;65(7):320-326. doi: 10.17221/76/2019-VETMED.
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    References

    1. Bertranou EG, Blackstone EH, Hazelrig JB, Turner ME, Kirklin JW. Life expectancy without surgery in tetralogy of Fallot. Am J Cardiol. 1978 Sep;42(3):458-66. Go to original source... Go to PubMed...
    2. Bussadori C, Pradelli D. Congenital cardiopathies. In: de Madron E, Bussadori C, Chetboul V, editors. Clinical echocardiography of the dog and cat. Saint Louis, Mo: Elsevier; 2015. p. 285-322. Go to original source...
    3. Fukushima R, Yoshiyuki R, Machida N, Matsumoto H, Kim S, Hamabe L, Huai-Che H, Fukayama T, Suzuki S, Aytemiz D, Tanaka R, Yamane Y. Extreme tetralogy of Fallot in a dog. J Vet Med Sci. 2013;75(8):1111-4. Go to original source... Go to PubMed...
    4. Karl TR, Stocker C. Tetralogy of Fallot and its variants. Pediatr Crit Care Med. 2016 Aug;17(8 Suppl 1):S330-6. Go to original source... Go to PubMed...
    5. Kim J, Bae Y, Lee G, Jeon S, Choi J. Dynamic computed tomographic determination of scan delay for use in performing cardiac angiography in clinically normal dogs. Am J Vet Res. 2015 Aug;76(8):694-701. Go to original source... Go to PubMed...
    6. Murthy K, Reddy KP, Nagarajan R, Goutami V, Cherian K. Management of ventricular septal defect with pulmonary atresia and major aorto pulmonary collateral arteries: Challenges and controversies. Ann Pediatr Cardiol. 2010 Jul;3(2):127-35. Go to original source... Go to PubMed...
    7. Neches WH, Park SC, Ettedgui JA. Tetralogy of Fallot and tetralogy of Fallot with pulmonary atresia. In: Garson A, Bricker JT, McNamara DG, editors. The science and practice of pediatric cardiology. Philadelphia: Lea & Febiger; 1990. p. 1073-100.
    8. Park KS, Kim DY. The major aortopulmonary collateral arteries in pulmonary atresia with ventricular septal defect: Chest radiologic findings. Korean J Radiol. 1992 Nov; 28(6):875-80. Go to original source...
    9. Patterson DF, Pyle RL, Van Mierop L, Melbin J, Olson M. Hereditary defects of the conotruncal septum in Keeshond dogs: Pathologic and genetic studies. Am J Cardiol. 1974 Aug;34(2):187-205. Go to original source... Go to PubMed...
    10. Shiraishi I, Yamamoto Y, Ozawa S, Kawakita A, Toiyama K, Tanaka T, Sakata K, Hayano T, Itoi T, Yamagishi M, Hamaoka K. Application of helical computed tomographic angiography with differential color imaging three-dimensional reconstruction in the diagnosis of complicated congenital heart diseases. J Thorac Cardiovasc Surg. 2003 Jan;125(1):36-9. Go to original source... Go to PubMed...
    11. Tou SP, Keene BW, Barker PC. Pulmonary atresia and ventricular septal defect with aortopulmonary collaterals in an adult dog. J Vet Cardiol. 2011 Dec;13(4):271-5. Go to original source... Go to PubMed...
    12. van Praagh R. The first Stella van Praagh memorial lecture: The history and anatomy of tetralogy of Fallot. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2009:19-38. Go to original source... Go to PubMed...

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