Archives of Histology and Cytology
Online ISSN : 1349-1717
Print ISSN : 0914-9465
ISSN-L : 0914-9465
Original articles
Histology of the hepatopancreas of puffer fish (Takifugu rubripes) in relation to the localization of tetrodotoxin
Mitsutaka Miura, Yoshihiro Mezaki, Mayako Morii, Taku Hebiguchi, Hiroaki Yoshino, Kentaro Kawatsu, Mutsunori Fujiwara, Katsuyuki Imai, Haruki Senoo
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2013 Volume 74 Issue 1 Pages 59-70

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Abstract

The “liver” of puffer fish had both a hepatic portion and a pancreatic portion. The hepatic portion had the parenchyma and the portal area as mammalian livers such as human or mouse or rat. However, the hepatic lobule was not obvious histologically in the puffer liver. In the hepatic parenchyma, both parenchymal cells (hepatocytes) and non-parenchymal cells such as liver sinusoidal endothelial cells and hepatic stellate cells (vitamin A-storing cells, Ito cells) were demonstrated to exist. Cytoplasm of the parenchymal cells was filled with large fat droplets, namely, the liver was in steatosis, but neither hepatic fibrosis nor liver cirrhosis was identified. In the pancreatic portion, pancreatic acinar cells containing

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© 2013 by International Society of Histology and Cytology
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Archivum histologicum japonicum

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