Medio ambiente, comportamento y aprendizaje en ratones adultos

Garcia-Segura, Luis Miguel

doi:10.1590/S0004-282X1977000100006

Resúmenes

Se analiza el efecto que tiene sobre el ratón adulto el ser sometido a diferentes situaciones ambientales. Para ello se colocan ratones adultos en grupos de 12 en cajas que contienen rampas, pasarelas, pasadizos y objetos diversos, que se cambiaban de posición relativa varias veces por semana. Otros ratones se colocaron en grupos de 4 en cajas más pequenas y sin ninguno de estos objetos. Despues de estar 60 dias en estas condiciones se estúdio el comportamiento explorador de los ratones y su capacidad de aprendizaje de un laberinto complejo. Se observó una diferencia significativa entre los dos grupos de ratones ,tanto en su comportamiento explorador como en el tiempo empleado en resolver el laberinto y el número de ratones que lo resolvian en cada una de 10 pruebas sucesivas.

The effet that being subjected to different environmental situations has in the adult mouse is analysed. Adult mice are placed for that, in groups of twelve mice in cages that contains ramps, catwalks, passages, sleeping boxes and play objects, that were changed in their relative position several times in the week. Oth er mice were placed in groups of four mice in smaller boxes and without these objects. After 60 days in these conditions mice's exploratory behaviour and their learning ability in a complex maze were studied. A significant difference was observed between these two groups, as much in their exploratory behaviour as in the time spent on resolving maze, and the number of mice that resolved it in every one of ten sucesive trials.

Medio ambiente, comportamento y aprendizaje en ratones adultos

Environmental condictions, behaviour and learning in adult rats

Meio ambiente, comportamento e aprendizagem em ratos adultos

Luis Miguel Garcia-Segura

Instituto Cajal, C.S.I.C. - Madrid 6, Espana

RESUMEN

Se analiza el efecto que tiene sobre el ratón adulto el ser sometido a diferentes situaciones ambientales. Para ello se colocan ratones adultos en grupos de 12 en cajas que contienen rampas, pasarelas, pasadizos y objetos diversos, que se cambiaban de posición relativa varias veces por semana. Otros ratones se colocaron en grupos de 4 en cajas más pequenas y sin ninguno de estos objetos. Despues de estar 60 dias en estas condiciones se estúdio el comportamiento explorador de los ratones y su capacidad de aprendizaje de un laberinto complejo. Se observó una diferencia significativa entre los dos grupos de ratones ,tanto en su comportamiento explorador como en el tiempo empleado en resolver el laberinto y el número de ratones que lo resolvian en cada una de 10 pruebas sucesivas.

SUMMARY

The effet that being subjected to different environmental situations has in the adult mouse is analysed. Adult mice are placed for that, in groups of twelve mice in cages that contains ramps, catwalks, passages, sleeping boxes and play objects, that were changed in their relative position several times in the week. Oth er mice were placed in groups of four mice in smaller boxes and without these objects. After 60 days in these conditions mice's exploratory behaviour and their learning ability in a complex maze were studied. A significant difference was observed between these two groups, as much in their exploratory behaviour as in the time spent on resolving maze, and the number of mice that resolved it in every one of ten sucesive trials.

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

Agradecimientos - El autor agradece al Profesor A. Fernandez de Molina y a la Doctora M. Pilar Santaca na la lectura y sugerencias sobre el manuscrito de este trabajo.

Instituto Cajal - Consejo Superior de Investigaciones Cientificas - Call 4Velazquez 144 - Madrid-6, España.

1. ADER, R. - The effects of early experience on subsequent emotionality and resistance to stress. Psychol. Monog. 73: 1, 1969.
2. BARON, A. - Suppresion of exploratory behaviour by aversive stimulation. J. Comp. physiol. psychol. 57: 299, 1964.
3. BENNETT, E. L.; DIAMOND, M. C; KRECH, D. & ROSENZWEIG, M. R. - Chemical and anatomical plasticity of brain. Science 146 : 610, 1964.
4. BERSTEIN, L. - The effects of variance in handling upon learning and retention. J. Comp. physiol. psychol. 50: 162, 1957.
5. BLAKEMORE, C. & MITCHELL, D. E. - Environmental modification of the visual cortex and the neural basis of learning and memory. Nature (London) 241: 467, 1973.
6. DAVENPORT, J. W.; GONZALEZ, L. M.; CAREY, J. C; BISHOP, S. B. & HAGQUIST, W. W. - Environmental stimulation reduces learning deficits in experimental cretinism. Science 191: 578, 1976.
7. DAWSON, W. W. & HOFFMAN, C. S. - The effects of early differential environments on certain behaviour pattern in the albino rat. Psych. Rec. U.S.A. 8: 87, 1958.
8. DEFEUDIS, F. V.; OJEDA, A.; MADTES, P. & DEFEUNDS, P. A. - Environmentaly sensitive cerebral nerve ending. Naturwiss. 12 : 585, 1975.
9. DENELSKY, S. Y. & DENENBERG, V. H. - Infantile stimulation and adult exploratory behaviour in the rat: effects of handling on visual variation seeking. Anim. Behav. 15: 568, 1967.
10. DENELSKY, G. Y. & DENENBERG, V. H. - Infantile stimulation and adult exploratory behaviour: effects of handling upon tectal variation seeking. J. Comp. physiol. psychol. 63: 309, 1967.
11. DENENBERG, V. H. & BELL, R. W. - Critical periods for the effects of infantile experience on adult learning. Science 131: 227, 1960.
12. DENENBERG, V. H. & SMITH, S. A. - Effects of infantile stimulation and age upon behaviour. J. Comp. physiol. psychol. 56 : 307, 1963.
13. DENENBERG, V. H.; MORTON, J. R. C.; KLINE, N. J. & GROTA, L. J. - Effects of duration of infantile stimulation upon emotionality. Canad. J. Psychol. 16: 72, 1962.
14. DIAMOND, M. C.; LAW, F.; RHODES, H.; LINDER, B.; ROSENZWEIG, M. R.; KRECH, D. & BENNETT, E. I. - Increases in cortical depth and glia numbers in rats subjected to enriched environment. J. Comp. Neurol. 128; 117, 1966.
15. EHRLICH, A. - Effects of past experience on exploratory behaviour in rats. Can. J. Psychol. 13: 248, 1959.
16. EHRLICH, A. - Effects of past experience on rats response to novelty. Can. J. Psychol. 15: 15, 1961.
17. FIFKOVA, E. - Changes in the visual cortex of rats after unilateral deprivation. Nature (London) 220: 379, 1968.
18. FREDERICSON, E. - Competition: the effects of infantile experience upon adult behaviour. J. Abnorm. Soc. Psychol. 46 : 406, 1951.
19. FREEMAN, R. D. & PETTIGREW, J. D. - Alteration of visual cortex from environmental asymetries. Nature (London) 246 : 359, 1973.
20. GARCIA-SEGURA, L. M. - Cambios estructurales en el cerebro frente a la experiencia y su relación con la memoria y el aprendizaje. Arch. Neurobiol., 37: 561, 1974.
21. GARCIA-SEGURA, L. M. - Regulación ejercida por la experiencia en el desarrollo cerebral. Revisión. Rev. Psiquiatria y Psicologia Medica 12:49, 1975.
22. GARCIA-SEGURA, L. M. - Concepto dinámico del sistema nervioso. An. de Medicina y Cirurgia 55:321, 1975.
23. GARCIA-SEGURA, L. M. - La base molecular de la memoria y el aprendizaje. Rev.Neurologia 10:73, 1975.
24. GARCIA-SEGURA, L. M. - Papel de las proteinas en la memoria. Arch, Neurobiol. 38:199, 1975.
25. HINDE, R. A. - Animal Behaviour. McGraw-Hill Book Co., New York, 1966.
26. HOFFMAN, C. S. - Effects of early environmental restriction on subsequent behaviour in the rat. Psychol. Rec. U.S.A. 9: 171, 1969.
27. INGLIS, I. R. - Enriched sensory experience in adulthood increases subsequent exploratory behaviour in the rat. Anim. Behav. 23 : 932, 1975.
28. KING, J. A. & GURNEY, N. L. - Effect of early experience on adult behaviour in C5710 mice. J. Comp. physiol. psychol. 47 : 326, 1954.
29. KING, J. A. & ELEFTHERIOU, B. E. - Effects of early handling upon adult behaviour in two subspecies of deermice, Peromyscus maniculatus. J. Comp. physiol. psychol. 52 : 82, 1959.
30. LEVINE, S. A. - Emotionality and agressive behaviour in the mouse as a function of infantile experience. Amer. Psychologist. 12 : 410, 1957.
31. LEVINE, S. A. - Infantile experience and consumatory behaviour in adulthood. J. Comp. physiol. psychol. 50 : 609, 1957.
32. MARX, M. H. - Infantile deprivation and adult behaviour in the rat: retention of increased rats of eating. J. Comp. physiol. psychol. 45: 43, 1952.
33. Mc CALL, R. B. & LESTER, M. L. - Diferential enrichment potential of visual experience with angles versus curves. J. Comp. physiol. psychol. 69 : 644, 1969.
34. MONTGOMERY, K. C. & MONKMAN, J. A. - The relation between fear and exploratory behaviour. J. Comp. physiol. psychol. 48: 132, 1965.
35. MONTGOMERY, K. C. & ZIMBARDO, P. G. - Effects of sensory and behavioural deprivation upon exploratory behaviour in the rat. Percept. Mot. Skills 7: 223, 1957.
36. PARNAVELAS, J. G.; GLOBUS, A. & KAUPS, P. - Changes in lateral geniculate neurons of rats as a result of continuous exposure to light. Nature New Biol. (London) 245: 287, 1973.
37. ROSEN, J. - Dominance behaviour of the jult rat as a function of early social experience. J. Genet. Psychol. 99: 145, 1961.
38. SEITZ, P. F. D. - The effect of infantile experience upon adult behaviour in animal subjects: effects of litters size during infancy upon behaviour in the rat. Amer. J. Psychiatr. 110 : 916, 1954.
39. SEITZ, P. F. D. - Infantile experience and adult behaviour in animal: age of separation from mother and adult behaviour in the rat. Psychosom. Med. 21: 353, 1959.
40. SOSKIN, R. A. - The effect of early experience upon the formation of environmental preference in rats. J. Comp. Physiol. Psychol. 53: 303, 1963.
41. TEES, R. C. - Effect of early restriction on subsequent activity and emotionality in the rat. J. Genet. Psychol. 114: 193, 1969.
42. VALVERDE, F. - Apical dendritic spines of the visual cortex and light deprivation in the mouse. Exp. Brain. Res. 3: 337, 1967.
43. WEININGER, O. - The effects of early experience on behaviour and growth characteristics. J. Comp. Physiol. Psychol. 49: 1, 1956.
44. WELLS, P. A.; LOWE, G.; SHELTON, M. H. & WILLIAMS, D. I. - Effects of infantile stimulation and experimental familiarity on exploratory behaviour in the rat. Brith. J. Psychol. 50: 389, 1969.
45. WOLKMAR, F. R. & GREENOUGH, W. T. - Rearing complexity effects branching of dendrites in the visual cortex of rat. Science 176: 1445, 1972.
46. WOODS, P. J.; RUCKELHAUS, S. T. & BOWLING, D. M. - Some effects of "free" and "restricted" environmental rearing conditions upon adult behaviour in the rat Psychol. Rep. 6: 191, 1960.
47. ZIMBARDO, P. G. & MONTGOMERY, K. C. - Effects of "free-environment" rearing upon exploratory behaviour. Psychol. Rep. 3: 589, 1967.

Fechas de Publicación

Publicación en esta colección
30 Ago 2012
Fecha del número
Mar 1977

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. ADER, R. - The effects of early experience on subsequent emotionality and resistance to stress. Psychol. Monog. 73: 1, 1969.

[2] 2. BARON, A. - Suppresion of exploratory behaviour by aversive stimulation. J. Comp. physiol. psychol. 57: 299, 1964.

[3] 3. BENNETT, E. L.; DIAMOND, M. C; KRECH, D. & ROSENZWEIG, M. R. - Chemical and anatomical plasticity of brain. Science 146 : 610, 1964.

[4] 4. BERSTEIN, L. - The effects of variance in handling upon learning and retention. J. Comp. physiol. psychol. 50: 162, 1957.

[5] 5. BLAKEMORE, C. & MITCHELL, D. E. - Environmental modification of the visual cortex and the neural basis of learning and memory. Nature (London) 241: 467, 1973.

[6] 6. DAVENPORT, J. W.; GONZALEZ, L. M.; CAREY, J. C; BISHOP, S. B. & HAGQUIST, W. W. - Environmental stimulation reduces learning deficits in experimental cretinism. Science 191: 578, 1976.

[7] 7. DAWSON, W. W. & HOFFMAN, C. S. - The effects of early differential environments on certain behaviour pattern in the albino rat. Psych. Rec. U.S.A. 8: 87, 1958.

[8] 8. DEFEUDIS, F. V.; OJEDA, A.; MADTES, P. & DEFEUNDS, P. A. - Environmentaly sensitive cerebral nerve ending. Naturwiss. 12 : 585, 1975.

[9] 9. DENELSKY, S. Y. & DENENBERG, V. H. - Infantile stimulation and adult exploratory behaviour in the rat: effects of handling on visual variation seeking. Anim. Behav. 15: 568, 1967.

[10] 10. DENELSKY, G. Y. & DENENBERG, V. H. - Infantile stimulation and adult exploratory behaviour: effects of handling upon tectal variation seeking. J. Comp. physiol. psychol. 63: 309, 1967.

[11] 11. DENENBERG, V. H. & BELL, R. W. - Critical periods for the effects of infantile experience on adult learning. Science 131: 227, 1960.

[12] 12. DENENBERG, V. H. & SMITH, S. A. - Effects of infantile stimulation and age upon behaviour. J. Comp. physiol. psychol. 56 : 307, 1963.

[13] 13. DENENBERG, V. H.; MORTON, J. R. C.; KLINE, N. J. & GROTA, L. J. - Effects of duration of infantile stimulation upon emotionality. Canad. J. Psychol. 16: 72, 1962.

[14] 14. DIAMOND, M. C.; LAW, F.; RHODES, H.; LINDER, B.; ROSENZWEIG, M. R.; KRECH, D. & BENNETT, E. I. - Increases in cortical depth and glia numbers in rats subjected to enriched environment. J. Comp. Neurol. 128; 117, 1966.

[15] 15. EHRLICH, A. - Effects of past experience on exploratory behaviour in rats. Can. J. Psychol. 13: 248, 1959.

[16] 16. EHRLICH, A. - Effects of past experience on rats response to novelty. Can. J. Psychol. 15: 15, 1961.

[17] 17. FIFKOVA, E. - Changes in the visual cortex of rats after unilateral deprivation. Nature (London) 220: 379, 1968.

[18] 18. FREDERICSON, E. - Competition: the effects of infantile experience upon adult behaviour. J. Abnorm. Soc. Psychol. 46 : 406, 1951.

[19] 19. FREEMAN, R. D. & PETTIGREW, J. D. - Alteration of visual cortex from environmental asymetries. Nature (London) 246 : 359, 1973.

[20] 20. GARCIA-SEGURA, L. M. - Cambios estructurales en el cerebro frente a la experiencia y su relación con la memoria y el aprendizaje. Arch. Neurobiol., 37: 561, 1974.

[21] 21. GARCIA-SEGURA, L. M. - Regulación ejercida por la experiencia en el desarrollo cerebral. Revisión. Rev. Psiquiatria y Psicologia Medica 12:49, 1975.

[22] 22. GARCIA-SEGURA, L. M. - Concepto dinámico del sistema nervioso. An. de Medicina y Cirurgia 55:321, 1975.

[23] 23. GARCIA-SEGURA, L. M. - La base molecular de la memoria y el aprendizaje. Rev.Neurologia 10:73, 1975.

[24] 24. GARCIA-SEGURA, L. M. - Papel de las proteinas en la memoria. Arch, Neurobiol. 38:199, 1975.

[25] 25. HINDE, R. A. - Animal Behaviour. McGraw-Hill Book Co., New York, 1966.

[26] 26. HOFFMAN, C. S. - Effects of early environmental restriction on subsequent behaviour in the rat. Psychol. Rec. U.S.A. 9: 171, 1969.

[27] 27. INGLIS, I. R. - Enriched sensory experience in adulthood increases subsequent exploratory behaviour in the rat. Anim. Behav. 23 : 932, 1975.

[28] 28. KING, J. A. & GURNEY, N. L. - Effect of early experience on adult behaviour in C5710 mice. J. Comp. physiol. psychol. 47 : 326, 1954.

[29] 29. KING, J. A. & ELEFTHERIOU, B. E. - Effects of early handling upon adult behaviour in two subspecies of deermice, Peromyscus maniculatus. J. Comp. physiol. psychol. 52 : 82, 1959.

[30] 30. LEVINE, S. A. - Emotionality and agressive behaviour in the mouse as a function of infantile experience. Amer. Psychologist. 12 : 410, 1957.

[31] 31. LEVINE, S. A. - Infantile experience and consumatory behaviour in adulthood. J. Comp. physiol. psychol. 50 : 609, 1957.

[32] 32. MARX, M. H. - Infantile deprivation and adult behaviour in the rat: retention of increased rats of eating. J. Comp. physiol. psychol. 45: 43, 1952.

[33] 33. Mc CALL, R. B. & LESTER, M. L. - Diferential enrichment potential of visual experience with angles versus curves. J. Comp. physiol. psychol. 69 : 644, 1969.

[34] 34. MONTGOMERY, K. C. & MONKMAN, J. A. - The relation between fear and exploratory behaviour. J. Comp. physiol. psychol. 48: 132, 1965.

[35] 35. MONTGOMERY, K. C. & ZIMBARDO, P. G. - Effects of sensory and behavioural deprivation upon exploratory behaviour in the rat. Percept. Mot. Skills 7: 223, 1957.

[36] 36. PARNAVELAS, J. G.; GLOBUS, A. & KAUPS, P. - Changes in lateral geniculate neurons of rats as a result of continuous exposure to light. Nature New Biol. (London) 245: 287, 1973.

[37] 37. ROSEN, J. - Dominance behaviour of the jult rat as a function of early social experience. J. Genet. Psychol. 99: 145, 1961.

[38] 38. SEITZ, P. F. D. - The effect of infantile experience upon adult behaviour in animal subjects: effects of litters size during infancy upon behaviour in the rat. Amer. J. Psychiatr. 110 : 916, 1954.

[39] 39. SEITZ, P. F. D. - Infantile experience and adult behaviour in animal: age of separation from mother and adult behaviour in the rat. Psychosom. Med. 21: 353, 1959.

[40] 40. SOSKIN, R. A. - The effect of early experience upon the formation of environmental preference in rats. J. Comp. Physiol. Psychol. 53: 303, 1963.

[41] 41. TEES, R. C. - Effect of early restriction on subsequent activity and emotionality in the rat. J. Genet. Psychol. 114: 193, 1969.

[42] 42. VALVERDE, F. - Apical dendritic spines of the visual cortex and light deprivation in the mouse. Exp. Brain. Res. 3: 337, 1967.

[43] 43. WEININGER, O. - The effects of early experience on behaviour and growth characteristics. J. Comp. Physiol. Psychol. 49: 1, 1956.

[44] 44. WELLS, P. A.; LOWE, G.; SHELTON, M. H. & WILLIAMS, D. I. - Effects of infantile stimulation and experimental familiarity on exploratory behaviour in the rat. Brith. J. Psychol. 50: 389, 1969.

[45] 45. WOLKMAR, F. R. & GREENOUGH, W. T. - Rearing complexity effects branching of dendrites in the visual cortex of rat. Science 176: 1445, 1972.

[46] 46. WOODS, P. J.; RUCKELHAUS, S. T. & BOWLING, D. M. - Some effects of "free" and "restricted" environmental rearing conditions upon adult behaviour in the rat Psychol. Rep. 6: 191, 1960.

[47] 47. ZIMBARDO, P. G. & MONTGOMERY, K. C. - Effects of "free-environment" rearing upon exploratory behaviour. Psychol. Rep. 3: 589, 1967.

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Medio ambiente, comportamento y aprendizaje en ratones adultos

Environmental condictions, behaviour and learning in adult rats

Meio ambiente, comportamento e aprendizagem em ratos adultos

Resúmenes

Fechas de Publicación