Functional Connectivity and Small-World Networks in Prion Disease

Chisho TAKEOKA; Toshimasa YAMAZAKI; Yoshiyuki KUROIWA; Kimihiro FUJINO; Toshiaki HIRAI; Hidehiro MIZUSAWA

doi:10.1587/transinf.2022EDL8049

Regular Section

Functional Connectivity and Small-World Networks in Prion Disease

Chisho TAKEOKA, Toshimasa YAMAZAKI, Yoshiyuki KUROIWA, Kimihiro FUJINO, Toshiaki HIRAI, Hidehiro MIZUSAWA

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Keywords: dementia, prion disease, EEG, brain functional connectivity network, graph theory

JOURNAL FREE ACCESS

2023 Volume E106.D Issue 3 Pages 427-430

DOI https://doi.org/10.1587/transinf.2022EDL8049

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Abstract

We characterized prion disease by comparing brain functional connectivity network (BFCN), which were constructed by 16-ch scalp-recorded electroencephalograms (EEGs). The connectivity between each pair of nodes (electrodes) were computed by synchronization likelihood (SL). The BFCN was applied to graph theory to discriminate prion disease patients from healthy elderlies and dementia groups.

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