This brief proposes a solar-cell-assisted wireless biosensing system that operates using a biofuel cell (BFC). To facilitate BFC area reduction for the use of this system in area-constrained continuous glucose monitoring contact lenses, an energy harvester combined with an on-chip solar cell is introduced as a dedicated power source for the transmitter. A dual-oscillator-based supply voltage monitor is employed to convert the BFC output into digital codes. From measurements of the test chip fabricated in 65-nm CMOS technology, the proposed system can achieve 99% BFC area reduction.