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Green synthesis and antibacterial activity of hydroxyapatite nanorods for orthopedic applications

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Abstract

Biomaterials with antibacterial activity are widely developed for the treatment of bone infection. In the present study, hydroxyapatite (HAp) nanorods were prepared by green synthesis using Azadirachta indica and Coccinia grandis leaf extract. The prepared samples were characterized by various characterization techniques and the results indicate that the prepared samples are constituted of phase pure polycrystalline HAp having hexagonal crystal structure. Moreover, antibacterial activity test confirm that the HAp prepared using leaf extract as a solvent having significant antibacterial activity against Escherichia coli and Staphylococcus aureus. Hence, green synthesis can be a prospective way to develop orthopedic biomaterials with antibacterial properties.

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Acknowledgments

Dr. Govindan Suresh Kumar would like to express his sincere thanks to the University Grant Commission, India for financial support through minor research project scheme [File No: 4-4/2015-16 (MRP/UGC SERO)]. The work was carried out with financial support from the Ministry of Education and Science of the Russian Federation in the framework of Increase Competitiveness Program of NUST “MISiS”, implemented by a governmental decree dated 16th of March 2013, N 211.

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Authors and Affiliations

  1. Department of Physics, K.S. Rangasamy College of Arts and Science (Autonomous), Tiruchengode 637 215, Tamil Nadu, India

    Govindan Suresh Kumar, Senkotuvel Rajendran & Gopalu Karunakaran

  2. Department of Physics, Periyar University, Salem 636 011, Tamil Nadu, India

    Sekar Karthi, Raji Govindan & Easwaradas Kreedapathy Girija

  3. Department of Functional Nanosystems and High-Temperature Materials, National University of Science and Technology “MISiS,”, Leninskiy Pr. 4, Moscow, 119049, Russia

    Gopalu Karunakaran & Denis Kuznetsov

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  1. Govindan Suresh Kumar
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  2. Senkotuvel Rajendran
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  3. Sekar Karthi
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  4. Raji Govindan
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  5. Easwaradas Kreedapathy Girija
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  6. Gopalu Karunakaran
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  7. Denis Kuznetsov
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Correspondence to Govindan Suresh Kumar.

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Kumar, G.S., Rajendran, S., Karthi, S. et al. Green synthesis and antibacterial activity of hydroxyapatite nanorods for orthopedic applications. MRS Communications 7, 183–188 (2017). https://doi.org/10.1557/mrc.2017.18

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  • DOI: https://doi.org/10.1557/mrc.2017.18

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