Abstract
We show that the application of imaging and pattern recognition techniques developed for basic heavy ion research has useful applications in medical imaging. In particular, we utilize the fractal dimension of the perimeter surface of cell sections as a new observable to characterize cells of different types. We propose that it is possible to distinguish cancerous from healthy cells with the aid of this new approach. As a first application we show in an exploratory study that it is possible to perform this distinction between patients with hairy-cell lymphocytic leukemia and those with normal blood lymphocytes.
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Bauer, W., Mackenzie, C.D. Cancer detection on a cell-by-cell basis using a fractal dimension analysis. APH N.S., Heavy Ion Physics 14, 43–50 (2001). https://doi.org/10.1556/APH.14.2001.1-4.6
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DOI: https://doi.org/10.1556/APH.14.2001.1-4.6