Abstract
The covalent attachment of piperazine onto the inner walls of a microreactor using glycidyl methacrylate polymer brushes has been demonstrated. The piperazine-containing polymer brushes were first grown on a flat silicon oxide surface and were characterized by contact angle, Fourier transform infrared (FT-IR), ellipsometry, and X-ray photoelectron spectroscopy (XPS). The applicability of the catalytic polymer brushes in a microreactor was demonstrated for the Knoevenagel and nitroaldol condensation reactions, and the synthesis of coumarin derivatives. The catalytic activity of the microreactor was still intact even after 2 months.
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Munirathinam, R., Huskens, J. & Verboom, W. Piperazine-Containing Polymer Brush Layer as Supported Base Catalyst in a Glass Microreactor. J Flow Chem 4, 135–139 (2014). https://doi.org/10.1556/JFC-D-14-00020
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DOI: https://doi.org/10.1556/JFC-D-14-00020